Evidence map›Paper›PMID 32760005›Full record

ArticleNature2020

Position-specific oxidation of miR-1 encodes cardiac hypertrophy.

Heeyoung Seok, Haejeong Lee, Sohyun Lee, Seung Hyun Ahn, Hye-Sook Lee, Geun-Woo D Kim, Jongjin Peak, Jongyeun Park, You Kyung Cho, Yeojin Jeong and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 2 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Dysregulated mScience advances · 2026
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  20. o8G-modified circKIAA1797 promotes lung cancer development by inhibiting cuproptosis.Journal of experimental & clinical cancer research : CR · 2025
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Heeyoung SeokDepartment of Life Sciences, Korea University, Seoul, Korea.
Haejeong LeeDepartment of Life Sciences, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0001-5243-7595
Sohyun LeeDepartment of Life Sciences, Korea University, Seoul, Korea.
Seung Hyun AhnDepartment of Life Sciences, Korea University, Seoul, Korea.
Hye-Sook LeeDepartment of Life Sciences, Korea University, Seoul, Korea.
Geun-Woo D KimDepartment of Life Sciences, Korea University, Seoul, Korea.
Jongjin PeakDepartment of Life Sciences, Korea University, Seoul, Korea.
Jongyeun ParkDepartment of Life Sciences, Korea University, Seoul, Korea.
You Kyung ChoDepartment of Life Sciences, Korea University, Seoul, Korea.
Yeojin JeongDivision of Life Sciences, College of Life Sciences and Biotechnology, Korea University, Seoul, Korea.
Dowoon GuDepartment of Life Sciences, Korea University, Seoul, Korea.
Yeahji JeongDepartment of Life Sciences, Korea University, Seoul, Korea.ORCID http://orcid.org/0000-0003-0464-1422
Sangkyeong EomDepartment of Life Sciences, Korea University, Seoul, Korea.
Eun-Sook JangDepartment of Life Sciences, Korea University, Seoul, Korea.
Sung Wook ChiDepartment of Life Sciences, Korea University, Seoul, Korea. chi13@korea.ac.kr.ORCID http://orcid.org/0000-0002-8035-8242
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pathophysiology, reactive oxygen species oxidize biomolecules that contribute to disease phenotypes

Indexed as

Gene SilencingAnimalsBase PairingCardiomegalyCell LineDisease Models, AnimalGuanineHumansMiceMicroRNAsMyocytes, CardiacOxidation-ReductionRatsTranscription, GeneticTranscriptome8-hydroxyguanineGuanineMicroRNAsMIRN1 microRNA, human

Identifiers

PMID32760005
OpenAlexW3046979682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.