Evidence map›Paper›PMID 32760004›Full record

ArticleNature2020

Rescue of oxytocin response and social behaviour in a mouse model of autism.

Hanna Hörnberg, Enrique Pérez-Garci, Dietmar Schreiner, Laetitia Hatstatt-Burklé, Fulvio Magara, Stephane Baudouin, Alex Matter, Kassoum Nacro, Eline Pecho-Vrieseling, Peter Scheiffele

Open access · bronzeAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 1 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 1 synthesis or guideline pooled it, 157 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. International journal of molecular sciences · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. How does oxytocin modulate human behavior?Molecular psychiatry · 2025
    Review
  17. Article
  18. Neuroendocrine Control of Synaptic Transmission by PHAC-1 inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  19. Article
  20. Review

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Hanna HörnbergBiozentrum of the University of Basel, Basel, Switzerland.
Enrique Pérez-GarciDepartment of Biomedicine, University of Basel, Basel, Switzerland.
Dietmar SchreinerBiozentrum of the University of Basel, Basel, Switzerland.
Laetitia Hatstatt-BurkléBiozentrum of the University of Basel, Basel, Switzerland.
Fulvio MagaraCentre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.
Stephane BaudouinNeuroscience Division, School of Biosciences, Cardiff University, Cardiff, UK.
Alex MatterExperimental Drug Development Centre, Singapore, Singapore.
Kassoum NacroExperimental Drug Development Centre, Singapore, Singapore.ORCID http://orcid.org/0000-0002-3291-0215
Eline Pecho-VrieselingDepartment of Biomedicine, University of Basel, Basel, Switzerland.
Peter ScheiffeleBiozentrum of the University of Basel, Basel, Switzerland. peter.scheiffele@unibas.ch.ORCID http://orcid.org/0000-0002-9516-9399
University of Basel · CHExperimental Drug Development Centre · SGUniversity of Geneva · CHUniversity of Lausanne · CH

Funding

European Research CouncilSwiss National Science Foundation 140944Swiss National Science Foundation 160319
6 · The paper itself

Abstract

A fundamental challenge in developing treatments for autism spectrum disorders is the heterogeneity of the condition. More than one hundred genetic mutations confer high risk for autism, with each individual mutation accounting for only a small fraction of cases

Indexed as

Disease Models, AnimalSocial BehaviorAnimalsAutistic DisorderCell Adhesion Molecules, NeuronalEukaryotic Initiation Factor-4EMaleMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutMitogen-Activated Protein KinasesNerve Tissue ProteinsNeuronsOxytocinPhosphorylationCell Adhesion Molecules, NeuronalEukaryotic Initiation Factor-4EMembrane ProteinsMitogen-Activated Protein KinasesNerve Tissue Proteinsneuroligin 3OxytocinRNA, Messenger

Identifiers

PMID32760004
PMCPMC7116741
OpenAlexW3047544314

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.