Evidence map›Paper›PMID 32759956›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2021

Inhaled bronchodilator exposure in the management of bronchopulmonary dysplasia in hospitalized infants.

Joshua C Euteneuer, Ellen Kerns, Chelsey Leiting, Russell J McCulloh, Eric S Peeples

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. An Update on the Prevention and Management of Bronchopulmonary Dysplasia.Pediatric health, medicine and therapeutics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joshua C EuteneuerDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA.ORCID http://orcid.org/0000-0002-9059-0598
Ellen KernsDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA.
Chelsey LeitingChildren's Hospital & Medical Center, Omaha, NE, USA.
Russell J McCullohDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA.
Eric S PeeplesDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA. epeeples@childrensomaha.org.ORCID http://orcid.org/0000-0002-2892-2678
Children's Hospital & Medical Center · US

Funding

The Nebraska Pediatric Clinic Trials UnitUG1OD024953 · OD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Bradford A Brabec, Ellen Kerns · 2016 to 2026
$4.4M
NIH HHS UG1 OD024953
6 · The paper itself

Abstract

objectiveTo determine clinical, demographic, and hospital factors associated with inhaled bronchodilator (IB) use in infants with bronchopulmonary dysplasia (BPD) and specifically severe BPD. STUDY

designRetrospective multicenter cohort study of 4986 infants born <32 weeks gestation with developing BPD at 28 days of life. We used the Pediatric Health Information System database to compare hospital experience and the demographic and clinical characteristics of infants exposed and not exposed to IBs.

resultsTwenty-five percent of BPD patients (1224/4986) and 48% of severe BPD patients (664/1390) received IBs. IB exposure was higher in infants with the tracheostomy, prolonged steroid and diuretic exposure, and longer duration of respiratory support. IB use varied markedly between hospitals (0-59%). Average annual BPD census was not associated with IB use.

conclusionBronchodilator exposure is common in BPD patients with substantial variability in its use. Hospital experience did not account for the between-hospital variation in practice.

Indexed as

Bronchodilator AgentsBronchopulmonary DysplasiaChildCohort StudiesGestational AgeHumansInfantInfant, NewbornRetrospective StudiesBronchodilator Agents

Identifiers

PMID32759956
PMCPMC7404081
OpenAlexW3047220705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.