ArticleTranslational psychiatry2020
Electroconvulsive therapy modulates functional interactions between submodules of the emotion regulation network in major depressive disorder.
Article in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
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- Shared and Specific Patterns of Brain Functional Network Abnormalities in Patients With Idiopathic Dystonia and Across Subtypes.CNS neuroscience & therapeutics · 2026Article
- Changes in Neural Activities and Neuroplasticity Related to Nonpharmacological Interventions for Major Depressive Disorder: A Systematic Literature Review.Biological psychiatry global open science · 2025Review
- Genetic and molecular basis of abnormal BOLD signaling variability in patients with major depressive disorder after electroconvulsive therapy.Translational psychiatry · 2025Article
- Disrupted functional connectivity of the emotion regulation network in major depressive disorder and its association with symptom improvement: A multisite resting-state functional MRI study.Psychological medicine · 2025Article
- Shedding Light on the Aftermath: Childhood Maltreatment's Role in Modifying the Association Between Recent Life Stress and Resting-State Network Connectivity.Behavioral sciences (Basel, Switzerland) · 2024Article
- Molecular mechanisms underlying structural plasticity of electroconvulsive therapy in major depressive disorder.Brain imaging and behavior · 2024Article
- Motor dysfunction in Parkinson's patients: depression differences in a latent growth model.Frontiers in aging neuroscience · 2024Article
- Functional connectomics in depression: insights into therapies.Trends in cognitive sciences · 2023Review
- The role of ascending arousal network in patients with chronic insomnia disorder.Human brain mapping · 2023Article
- Cortico-basal ganglia networks dysfunction associated with disease severity in patients with idiopathic blepharospasm.Frontiers in neuroscience · 2023Article
- Noninvasive neuromodulation of the prefrontal cortex in mental health disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Understanding complex functional wiring patterns in major depressive disorder through brain functional connectome.Translational psychiatry · 2021Review
- Habenula and left angular gyrus circuit contributes to response of electroconvulsive therapy in major depressive disorder.Brain imaging and behavior · 2021Article
- Structural and Functional Abnormalities in Knee Osteoarthritis Pain Revealed With Multimodal Magnetic Resonance Imaging.Frontiers in human neuroscience · 2021Article
- Altered Dynamic Amplitude of Low-Frequency Fluctuations in Patients With Migraine Without Aura.Frontiers in human neuroscience · 2021Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
Abstract
An increasing number of neuroimaging studies have consistently revealed that disrupted functional interactions within the cognitive emotion regulation network (ERN) contribute to the onset of major depressive disorders (MDD). To disentangle the functional reorganization of ERN after electroconvulsive therapy (ECT) in MDD is curial for understanding its neuropathology. Resting-state functional magnetic resonance imaging data was collected from 23 MDD patients before and after ECT, as well as 25 healthy controls. Network modularity analysis was used to identify the submodules and functional connectivity (FC) was used to investigate the functional reorganization of ERN in the MDD patients after ECT. Four submodules of ERN were identified, including emotion response module (ERM), emotion integration module (EIM), emotion generation module (EGM), and emotion execution module (EEM). The increased intra-modular FC of EEM and inter-modular FCs of EEM with EIM\ERM were found in MDD patients after ECT. Modular transition analysis revealed that left ventrolateral prefrontal cortex, supplementary motor area, posterior cingulate cortex, right angular gyrus, and right precentral gyrus were transferred across different submodules across the three groups. Further analyses showed correlations between changed FC and clinical symptoms in the MDD patients after ECT. Finally, we also identified 11 increased connections between nodes belonging to different submodules of ERN in MDD patients after ECT. These results showed that ECT could induce functional reorganization of intra- and inter-modules within the ERN, and the functional changes were related to therapeutic efficacy or memory impairments of ECT in MDD patients.
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