Evidence map›Paper›PMID 32759847›Full record

ArticleInternational journal of molecular sciences2020

Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore.

Hitomi Koga, Mai Negishi, Marie Kinoshita, Shinya Fujii, Shuichi Mori, Mari Ishigami-Yuasa, Emiko Kawachi, Hiroyuki Kagechika, Aya Tanatani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. WTAP-mediated mScience China. Life sciences · 2025
    Article
  3. Anti-Alopecia Activity of Coumarin Derivatives Isolated fromPharmaceuticals (Basel, Switzerland) · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hitomi KogaDepartment of Chemistry, Faculty of Science, Ochanomizu University, 2-1-1 Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan.
Mai NegishiDepartment of Chemistry, Faculty of Science, Ochanomizu University, 2-1-1 Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan.
Marie KinoshitaDepartment of Chemistry, Faculty of Science, Ochanomizu University, 2-1-1 Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan.
Shinya FujiiInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Shuichi MoriInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Mari Ishigami-YuasaInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Emiko KawachiInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Hiroyuki KagechikaInstitute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.ORCID 0000-0002-6747-1013
Aya TanataniDepartment of Chemistry, Faculty of Science, Ochanomizu University, 2-1-1 Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan.ORCID 0000-0002-6667-8506
Tokyo Medical and Dental University · JPOtsuka (Japan) · JP

Funding

Japan Agency for Medical Research and Development JP19am0101098JSPS KAKENHI 20K06963, 17H03887, 19K22486
6 · The paper itself

Abstract

First-generation nonsteroidal androgen receptor (AR) antagonists, such as flutamide (

Indexed as

Androgen Receptor AntagonistsAndrogensCell Line, TumorCell ProliferationCoumarinsFlutamideHumansMaleMolecular StructureMutationNonsteroidal Anti-AndrogensProstate-Specific AntigenProstatic NeoplasmsProstatic Neoplasms, Castration-ResistantReceptors, AndrogenAndrogen Receptor AntagonistsAndrogensCoumarinsFlutamidehydroxyflutamideNonsteroidal Anti-AndrogensProstate-Specific AntigenReceptors, Androgencell proliferationcis-amidecoumarinprostate cancer

Identifiers

PMID32759847
PMCPMC7432827
OpenAlexW3047504891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.