Evidence map›Paper›PMID 32759795›Full record

ArticleInternational journal of molecular sciences2020

Comprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic Cancer.

Shashi Anand, Mohammad Aslam Khan, Moh'd Khushman, Santanu Dasgupta, Seema Singh, Ajay Pratap Singh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Rab GTPases: Central Coordinators of Membrane Trafficking in Cancer.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shashi AnandDepartment of Pathology, College of Medicine, University of South Alabama, Mobile, AL 36617, USA.
Mohammad Aslam KhanDepartment of Pathology, College of Medicine, University of South Alabama, Mobile, AL 36617, USA.
Moh'd KhushmanDepartment of Medical Oncology, Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA.
Santanu DasguptaDepartment of Pathology, College of Medicine, University of South Alabama, Mobile, AL 36617, USA.
Seema SinghDepartment of Pathology, College of Medicine, University of South Alabama, Mobile, AL 36617, USA.
Ajay Pratap SinghDepartment of Pathology, College of Medicine, University of South Alabama, Mobile, AL 36617, USA.
USA Mitchell Cancer Institute · US

Funding

Impact of social factors on breast cancer biology in African-American womenR01CA231925 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SINGH, SEEMA · 2019 to 2023
$3.0M
Targeting tumor-stromal interaction for pancreatic cancer therapyR01CA175772 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SINGH, AJAY PRATAP · 2014 to 2018
$1.9M
Molecular causes and mechanistic underpinning of breast cancer racial disparityR01CA204801 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SINGH, SEEMA · 2016 to 2020
$1.7M
A novel molecular cross-talk driving pancreatic cancer progressionR01CA224306 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SINGH, AJAY PRATAP · 2018 to 2022
$1.7M
Molecular determinant of racial disparity in prostate cancerU01CA185490 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI SINGH, AJAY PRATAP · 2014 to 2018
$1.7M
NCI NIH HHS R01CA175772NCI NIH HHS R01CA204801NCI NIH HHS R01CA224306NCI NIH HHS R01CA231925NCI NIH HHS U01CA185490
6 · The paper itself

Abstract

RAB proteins (RABs) represent the largest subfamily of Ras-like small GTPases that regulate a wide variety of endosomal membrane transport pathways. Their aberrant expression has been demonstrated in various malignancies and implicated in pathogenesis. Using The Cancer Genome Atlas (TCGA) database, we analyzed the differential expression and clinicopathological association of

Indexed as

PrognosisAdenocarcinomaAdultAgedAged, 80 and overBiomarkers, TumorFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedMitochondrial ProteinsPancreatic NeoplasmsProgression-Free Survivalrab3A GTP-Binding Proteinrab GTP-Binding ProteinsBiomarkers, TumorMitochondrial ProteinsRAB21 protein, humanRAB22A protein, humanRab25 protein, humanRab26 protein, humanrab3A GTP-Binding ProteinRAB40AL protein, humanrab GTP-Binding ProteinsRABL2A protein, humanras Proteinsclinicopathologicalpancreatic cancerRAB family genesThe Human Protein AtlasUALCAN

Identifiers

PMID32759795
PMCPMC7432855
OpenAlexW3047018593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.