Evidence map›Paper›PMID 32759579›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Hepatitis B Virus-related Vasculitic Neuropathy in an Inactive Virus Carrier Treated with Intravenous Immunoglobulin.

Kaori Kusama, Yoshiharu Nakae, Mikiko Tada, Yuichi Higashiyama, Yosuke Miyaji, Genpei Yamaura, Misako Kunii, Kenichi Tanaka, Ken Ohyama, Haruki Koike and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Kaori KusamaDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Yoshiharu NakaeDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Mikiko TadaDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Yuichi HigashiyamaDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Yosuke MiyajiDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Genpei YamauraDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Misako KuniiDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Kenichi TanakaDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Ken OhyamaDepartment of Neurology, Nagoya University Graduate School of Medicine, Japan.
Haruki KoikeDepartment of Neurology, Nagoya University Graduate School of Medicine, Japan.
Hideto JokiDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Hiroshi DoiDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Shigeru KoyanoDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Fumiaki TanakaDepartment of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
Yokohama City University · JPNagoya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a 33-year-old woman who was an asymptomatic hepatitis B virus (HBV) carrier and presented with distal muscle weakness in the legs and asymmetrical paresthesia in the distal extremities. A nerve biopsy specimen revealed fibrinoid necrosis associated with inflammatory infiltration in the perineural space, and deposition of hepatitis B core antigen and C4d complement was detected in the vascular endothelial cells as well as around the vessels. She was diagnosed with HBV-related vasculitic neuropathy and treated with intravenous immunoglobulin (IVIG). Her symptoms completely subsided after eight weeks. Vasculitic neuropathy rarely develops in the chronic inactive stages of HBV infection. This is the first report of an HBV-inactive carrier with vasculitic neuropathy successfully treated with IVIG.

Indexed as

Carrier StateAdultEndothelial CellsFemaleHepatitis BHepatitis B virusHumansImmunoglobulins, IntravenousPeripheral Nervous System DiseasesVasculitisImmunoglobulins, Intravenoushepatitis B virus (HBV)intravenous immunoglobulin (IVIG)vasculitic neuropathy

Identifiers

PMID32759579
PMCPMC7759712
OpenAlexW3047534099

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.