ArticleThe Journal of veterinary medical science2020
Immunohistochemical analysis of periostin in the hearts of Lewis rats with experimental autoimmune myocarditis.
Article in The Journal of veterinary medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Histopathological evaluation of the lungs in experimental autoimmune encephalomyelitis.Journal of veterinary science · 2024Article
- Review
- Alendronate Enhances Functional Recovery after Spinal Cord Injury.Experimental neurobiology · 2022Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
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Abstract
Periostin plays a critical role in tissue regeneration and homeostasis. The aim of this study was to evaluate the changes in periostin levels in the hearts of rats with experimental autoimmune myocarditis (EAM). Western blot analysis revealed that the expression levels of periostin and alpha-smooth muscle actin were significantly increased at day 14 post-immunization. Immunohistochemical analysis indicated that periostin was expressed in macrophages and fibroblasts in the hearts of EAM-induced rats. In conclusion, these results suggest that increased periostin expression in macrophages and fibroblasts promotes cardiac fibrosis in EAM-induced rats, potentially by enhancing immune cell infiltration. Therefore, periostin should be further investigated as a candidate therapeutic target for myocarditis.
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