Evidence map›Paper›PMID 32759373›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2020

Airway mechanical compression: its role in asthma pathogenesis and progression.

Punnam Chander Veerati, Jennifer A Mitchel, Andrew T Reid, Darryl A Knight, Nathan W Bartlett, Jin-Ah Park, Chris L Grainge

Open access · diamondAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. The importance of mechanical forces in chronic respiratory diseases.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Global warming risks dehydrating and inflaming human airways.Communications earth & environment · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. The epithelium takes the stage in asthma and inflammatory bowel diseases.Frontiers in cell and developmental biology · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Punnam Chander VeeratiSchool of Medicine and Public Health, University of Newcastle, Callaghan, Australia.ORCID https://orcid.org/0000-0003-1612-0907
Jennifer A MitchelMolecular and Integrative Physiological Sciences Program, Dept of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Andrew T ReidSchool of Medicine and Public Health, University of Newcastle, Callaghan, Australia.
Darryl A KnightPriority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia.
Nathan W BartlettPriority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia.ORCID https://orcid.org/0000-0002-2715-5163
Jin-Ah ParkMolecular and Integrative Physiological Sciences Program, Dept of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Chris L GraingeSchool of Medicine and Public Health, University of Newcastle, Callaghan, Australia christopher.grainge@health.nsw.gov.au.
Hunter Medical Research Institute · AUJohn Hunter Hospital · AUUniversity of British Columbia · CA

Funding

Training Program in Molecular and Integrative Physiological SciencesT32HL007118 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LU, QUAN · 1985 to 2025
$14.3M
Physics of bronchial epithelial unjammingR01HL148152 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI FREDBERG, JEFFREY J, PARK, JIN-AH · 2019 to 2022
$2.2M
NHLBI NIH HHS R01 HL148152NHLBI NIH HHS T32 HL007118
6 · The paper itself

Abstract

The lung is a mechanically active organ, but uncontrolled or excessive mechanical forces disrupt normal lung function and can contribute to the development of disease. In asthma, bronchoconstriction leads to airway narrowing and airway wall buckling. A growing body of evidence suggests that pathological mechanical forces induced by airway buckling alone can perpetuate disease processes in asthma. Here, we review the data obtained from a variety of experimental models, including

Indexed as

AsthmaErbB ReceptorsGoblet CellsHumansModels, BiologicalRespiratory MucosaStress, MechanicalErbB Receptors

Identifiers

PMID32759373
PMCPMC8008491
OpenAlexW3047030607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.