Evidence map›Paper›PMID 32759361›Full record

ArticleDiabetes care2020

Reducing Inpatient Hypoglycemia in the General Wards Using Real-time Continuous Glucose Monitoring: The Glucose Telemetry System, a Randomized Clinical Trial.

Lakshmi G Singh, Medha Satyarengga, Isabel Marcano, William H Scott, Lillian F Pinault, Zhaoyong Feng, John D Sorkin, Guillermo E Umpierrez, Elias K Spanakis

4 registry-linked trialsOpen access · bronzeAbstract readComment
In one paragraph

Article in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 80 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 4 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03508934 naactive not recruitingnot on this map

Continuous Glucose Monitoring in Insulin Treated Hospitalized Veterans With DM2 at Higher Risk for Hypoglycemia

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2018 to 2026Enrolled218ConditionsDiabetes Mellitus, Type 2, HypoglycemiaArmsGTS (Continuous Glucose Monitoring), POC (Point of Care)
NCT05135676 nacompletednot on this mapstarted 2022, after this paper: background citation

Time in Glucose Hospital Target (TIGHT) - A Randomized Clinical Trial to Evaluate the Use of CGM to Achieve a Mean Glucose Target of 90 to 130 mg/dL Without Hypoglycemia in Hospitalized Adults With Type 2 Diabetes

TypeinterventionalSponsorJaeb Center for Health ResearchRan2022 to 2024Enrolled169ConditionsDiabetes Mellitus, Type 2ArmsBlinded CGM, real-time CGM
NCT06141941 nacompletednot on this mapstarted 2021, after this paper: background citation

Does the Use of Continuous Glucose Monitoring (CGM) in the Immediate Postpartum Period in Women With Pregestational Diabetes Admitted to the Hospital Decrease Hypoglycemic Episodes

TypeinterventionalSponsorUniversity of IowaRan2021 to 2024Enrolled39ConditionsPregestational DiabetesArmsCGM
NCT06614127 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Continuous Intraoperative Glucose Monitoring: A Pilot Study

TypeobservationalSponsorLoma Linda UniversityRan2024 to 2026Enrolled45ConditionsAnesthesiaArmsDexcom G7® sensor placed in upper arm and positioned over deltoid, Dexcom G7® sensor placed in lateral thigh
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 4 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
  2. Pooled it
  3. Guideline
  4. Guideline
  5. Trial
  6. Trial
  7. Randomized Study Comparing Continuous Glucose Monitoring and Capillary Glucose Testing in Patients With Type 2 Diabetes After Hospital Discharge.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Inpatient Use of Automated Insulin Delivery Systems.Journal of diabetes science and technology · 2026
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Lakshmi G SinghDivision of Endocrinology, Baltimore Veterans Affairs Medical Center, Baltimore, MD.
Medha SatyarenggaCenter for Diabetes and Endocrinology, University of Maryland Shore Regional Health, Easton, MD.
Isabel MarcanoDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD.
William H ScottDivision of Endocrinology, Baltimore Veterans Affairs Medical Center, Baltimore, MD.
Lillian F PinaultDivision of Endocrinology, Baltimore Veterans Affairs Medical Center, Baltimore, MD.
Zhaoyong FengPharmaceutical Research Computing, Department of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, MD.
John D SorkinBaltimore Veterans Affairs Medical Center Geriatric Research, Education, and Clinical Center, Baltimore, MD.
Guillermo E UmpierrezDivision of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA.ORCID 0000-0002-3252-5026
Elias K SpanakisDivision of Endocrinology, Baltimore Veterans Affairs Medical Center, Baltimore, MD ispanakis@som.umaryland.edu.ORCID 0000-0002-9352-7172
University of Maryland, Baltimore · USVeterans Health Administration · USEmory University · USGeriatric Research Education and Clinical Center · USUniversity of Maryland Eastern Shore · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Continuous Glucose Monitoring in Insulin Treated Hospitalized Veterans with DM2 at Higher Risk for HypoglycemiaI01CX001825 · VA · BALTIMORE VA MEDICAL CENTER · PI SPANAKIS, ILIAS · 2018 to 2023
–
CSRD VA I01 CX001825NCATS NIH HHS UL1 TR002378NIA NIH HHS P30 AG028747NIDDK NIH HHS P30 DK072488NIDDK NIH HHS P30 DK111024
6 · The paper itself

Abstract

objectiveUse of real-time continuous glucose monitoring (RT-CGM) systems in the inpatient setting is considered investigational. The objective of this study was to evaluate whether RT-CGM, using the glucose telemetry system (GTS), can prevent hypoglycemia in the general wards. RESEARCH DESIGN AND

methodsIn a randomized clinical trial, insulin-treated patients with type 2 diabetes at high risk for hypoglycemia were recruited. Participants were randomized to RT-CGM/GTS or point-of-care (POC) blood glucose testing. The primary outcome was difference in inpatient hypoglycemia.

resultsSeventy-two participants were included in this interim analysis, 36 in the RT-CGM/GTS group and 36 in the POC group. The RT-CGM/GTS group experienced fewer hypoglycemic events (<70 mg/dL) per patient (0.67 [95% CI 0.34-1.30] vs. 1.69 [1.11-2.58],

conclusionsRT-CGM/GTS can decrease hypoglycemia among hospitalized high-risk insulin-treated patients with type 2 diabetes.

Identifiers

PMID32759361
PMCPMC7576426
OpenAlexW3047317123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.