ArticleJournal of clinical microbiology2020
A Diagnostic Stewardship Intervention To Improve Blood Culture Use among Adult Nonneutropenic Inpatients: the DISTRIBUTE Study.
Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 66 citations in OpenAlex.
- Evaluation of a Direct-from-Blood Molecular Diagnostic Platform for Pathogen Detection in Critically Ill Patients: A Prospective Observational Cohort Study.Open forum infectious diseases · 2026Article
- Diagnostic disruption during a blood culture bottle shortage: clinical and laboratory adaptation strategies.Microbiology spectrum · 2026Observational
- Optimizing Resource Utilization in Low- and Middle-Income Country NICUs: A Clinical Audit of Surgical Infection Screening Practices at a High-Volume NICU in Pakistan.Pakistan journal of medical sciences · 2026Article
- Are SEP-1 and blood culture stewardship at odds? Retrospective review of SEP-1 failures pre- and during a blood culture bottle shortage.Infection control and hospital epidemiology · 2026Article
- A scoping review of interventions to improve blood culture sampling practices in hospital acute care settings.JAC-antimicrobial resistance · 2026Review
- Blood culture utilization and impact of stewardship practices during a national blood culture bottle shortage at a cancer center.Journal of clinical microbiology · 2026Article
- Drawing conclusions: blood culture yield across clinical scenarios in hematologic malignancy.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Enhancing the effectiveness of multidisciplinary interventions to improve blood culture efficiency and optimize antimicrobial utilization.Frontiers in public health · 2026Article
- Association Between Blood Culture Bottle Shortage and Ordering Restrictions and Clinical Outcomes for Patients WithOpen forum infectious diseases · 2025Article
- Article
- Factors associated with blood culture sampling for adult acute care hospital patients with suspected severe infection: a scoping review using a socioecological framework.JAC-antimicrobial resistance · 2025Review
- Blood Culture Use in Medical and Surgical Intensive Care Units and Wards.JAMA network open · 2025Article
- Implementation of blood culture stewardship during a blood culture bottle shortage: a multicenter assessment.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- A review of implementation aspects and sustainability in the prevention of hospital onset bacteremia.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Review
- The role of rapid multiplex molecular syndromic panels in the clinical management of infections in critically ill patients: an experts-opinion document.Critical care (London, England) · 2024Review
- Fine-tuning blood culture practices: implementing diagnostic stewardship in cardiothoracic surgery patients.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Rapid implementation of a clinical decision-support workflow during the national blood culture bottle shortage.Infection prevention in practice · 2024Article
- Every Crisis Is an Opportunity: Advancing Blood Culture Stewardship During a Blood Culture Bottle Shortage.Open forum infectious diseases · 2024Article
- Diagnostic stewardship in infectious diseases: a scoping review.Journal of medical microbiology · 2024Article
- Using interprofessional collaboration to reduce reported rates of central-line-associated bloodstream infection in an intensive care setting.Infection control and hospital epidemiology · 2024Article
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 1 country.
Funding
Abstract
Interventions to optimize blood culture (BCx) practices in adult inpatients are limited. We conducted a before-after study evaluating the impact of a diagnostic stewardship program that aimed to optimize BCx use in a medical intensive care unit (MICU) and five medicine units at a large academic center. The program included implementation of an evidence-based algorithm detailing indications for BCx use and education and feedback to providers about BCx rates and indication inappropriateness. Neutropenic patients were excluded. BCx rates from contemporary control units were obtained for comparison. The primary outcome was the change in BCxs ordered with the intervention. Secondary outcomes included proportion of inappropriate BCx, solitary BCx, and positive BCx. Balancing metrics included compliance with the Centers for Medicare and Medicaid Services (CMS) SEP-1 BCx component, 30-day readmission, and all-cause in-hospital and 30-day mortality. After the intervention, BCx rates decreased from 27.7 to 22.8 BCx/100 patient-days (PDs) in the MICU (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.