ArticleBMJ open2020
Incidence and risk factors of retinopathy of prematurity in Korle-Bu Teaching Hospital: a baseline prospective study.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Gestational Age-Specific Prevalence of Retinopathy of Prematurity in Very Preterm Infants: An Exploratory Meta-Analysis.Acta paediatrica (Oslo, Norway : 1992) · 2026Pooled it
- Prevalence and associated factors of retinopathy of prematurity in sub‑Saharan Africa: a systematic review and meta‑analysis.BMC ophthalmology · 2025Pooled it
- Effect of mode of delivery on incidence of retinopathy of prematurity: a systematic review and meta-analysis.BMJ open ophthalmology · 2024Pooled it
- Cost-Effectiveness of Telemedicine-Based Screening Programs for Retinopathy of Prematurity in Low- and Middle-Income Countries.Ophthalmology science · 2026Article
- Prevalence of retinopathy of prematurity in African preterm infants and evaluation of the accuracy of the WINROP predictive algorithm: an observational clinical study.BMC ophthalmology · 2025Observational
- Comparative Evaluation of Glycaemic and Non-Glycaemic Factors as Determinants of Retinopathy Status in an Adult Population: A Case-Control Study.Health science reports · 2025Article
- Prevalence and associated factors for retinopathy of prematurity at a tertiary hospital in Dar es Salaam, Tanzania.Eye (London, England) · 2025Article
- Deep learning applications for diabetic retinopathy and retinopathy of prematurity diseases diagnosis: a systematic review.International journal of ophthalmology · 2025Review
- Retinopathy of Prematurity in Eight Portuguese Neonatal Intensive Care Units: Incidence, Risk Factors, and Progression-A Prospective Multicenter Study.Children (Basel, Switzerland) · 2024Article
- [Global ophthalmology : Update].Die Ophthalmologie · 2024Article
- A Review on the Incidence and Related Risk Factors of Retinopathy of Prematurity Across Various Countries.Cureus · 2022Review
- Blindness Secondary to Retinopathy of Prematurity in Sub-Saharan Africa.Ophthalmic epidemiology · 2022Article
- Oxygen management among infants in neonatal units in sub-Saharan Africa: a cross-sectional survey.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Haemoglobin Levels in Early Life among Infants with and without Retinopathy of Prematurity.International journal of environmental research and public health · 2021Article
- Comparison of Mean Platelet Counts in Preterm Infants with and without Retinopathy of Prematurity.International journal of environmental research and public health · 2021Article
- Retinopathy of Prematurity in the University of Calabar Teaching Hospital, Calabar, Nigeria: An Early Report of a Screening Service.Journal of the West African College of SurgeonsArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the incidence of retinopathy of prematurity (ROP) and any associated risk factors among preterm infants at the Neonatal Intensive Care Unit (NICU) of Korle-Bu Teaching Hospital (KBTH).
designProspective study.
settingLevel 3 NICU of KBTH from June 2018 to February 2019.
participantsEligible infants with birth weight (BW) less than 2 kg or gestational age (GA) less than 37 weeks were examined at scheduled intervals until full maturity of their retina. OUTCOME MEASURES: The primary outcome measure was cumulative incidence of ROP and secondary outcome measure was risk factors associated with ROP.
resultsOf the 401 infants, 222 were females (55.4%), mean±SD GA was 32.3±2.4 weeks (median 32, IQR 31 to 34) and mean BW 1.6±0.4 kg (median 1.5, IQR 1.3 to 1.9). The cumulative incidence of ROP was 13.7% (95% CI: 10.5 to 17.5%), with 1.8% (seven infants) having type 1 ROP. Increased risk of ROP was observed in babies with supplemental oxygen exposure (p<0.001), BW less than 1.5 kg (p=0.019), confirmed neonatal sepsis (p=0.001), nasogastric tube feeding (p=0.03) and poor pupillary dilation (0.032). A reduced risk of ROP was observed in boys (p=0.004) and after delivery by caesarean section (p=0.019).
conclusionThe rates of ROP at KBTH are comparable to other NICUs in sub-Saharan Africa. Birth weight less than 1.5 kg, confirmed neonatal sepsis, nasogastric tube feeding and poor pupil dilation were independently associated with increased incidence of ROP. ROP screening should be a part of the routine service for premature infants in Ghana.
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