Evidence map›Paper›PMID 32759221›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments.

Fengbin Wang, Diana P Baquero, Leticia C Beltran, Zhangli Su, Tomasz Osinski, Weili Zheng, David Prangishvili, Mart Krupovic, Edward H Egelman

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. ICTV Virus Taxonomy Profile:The Journal of general virology · 2025
    Review
  3. Exploring Virus Taxonomy, Nomenclature, and Classification.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. The Expanding Diversity of Viruses from Extreme Environments.International journal of molecular sciences · 2024
    Review
  5. Diversity ofISME communications · 2024
    Article
  6. Article
  7. Article
  8. The evolution of archaeal flagellar filaments.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Viruses in astrobiology.Frontiers in microbiology · 2022
    Review
  14. Viruses Defined by the Position of the Virosphere within the Replicator Space.Microbiology and molecular biology reviews : MMBR · 2021
    Article
  15. Review
  16. Review
  17. A filamentous archaeal virus is enveloped inside the cell and released through pyramidal portals.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  18. Journal of virology · 2021
    Article
  19. ICTV Virus Taxonomy Profile:The Journal of general virology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Fengbin WangDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908.
Diana P BaqueroArchaeal Virology Unit, Department of Microbiology, Institut Pasteur, 75015 Paris, France.
Leticia C BeltranDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908.
Zhangli SuDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908.ORCID 0000-0001-6495-3351
Tomasz OsinskiDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908.ORCID 0000-0001-9933-346X
Weili ZhengDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908.
David PrangishviliArchaeal Virology Unit, Department of Microbiology, Institut Pasteur, 75015 Paris, France.
Mart KrupovicArchaeal Virology Unit, Department of Microbiology, Institut Pasteur, 75015 Paris, France; mart.krupovic@pasteur.fr egelman@virginia.edu.ORCID 0000-0001-5486-0098
Edward H EgelmanDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908; mart.krupovic@pasteur.fr egelman@virginia.edu.ORCID 0000-0003-4844-5212
University of Virginia · USInstitut Pasteur · FRTbilisi State University · GE

Funding

Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic ResolutionR35GM122510 · NIGMS · UNIVERSITY OF VIRGINIA · PI EDWARD H. EGELMAN · 2017 to 2026
$7.3M
NCI NIH HHS HHSN261200800001ENIGMS NIH HHS R35 GM122510
6 · The paper itself

Abstract

Living organisms expend metabolic energy to repair and maintain their genomes, while viruses protect their genetic material by completely passive means. We have used cryo-electron microscopy (cryo-EM) to solve the atomic structures of two filamentous double-stranded DNA viruses that infect archaeal hosts living in nearly boiling acid:

Indexed as

Archaeal VirusesBiological EvolutionCapsidDNA, ViralDNA VirusesExtreme EnvironmentsGenome, ViralPhylogenySulfolobalesSulfolobusDNA, Viralcryo-EMextremophilesfilamentous viruseshyperthermophilic archaea

Identifiers

PMID32759221
PMCPMC7443925
OpenAlexW3046927835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.