Evidence map›Paper›PMID 32759097›Full record

ArticleJBRA assisted reproduction2021

The Role of Inflammatory Hematological Markers in Predicting IVF Success.

A Seval Ozgu-Erdinc, Bugra Coskun, Ayçağ Yorganci, Necati Hancerliogullari, Nafiye Yilmaz, Yaprak Engin-Ustun

Abstract read
In one paragraph

Article in JBRA assisted reproduction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A Seval Ozgu-ErdincMinistry of Health Ankara City Hospital, Ankara, Turkey.
Bugra CoskunAnkara Liv Hospital, Ankara, Turkey.
Ayçağ YorganciMinistry of Health Ankara City Hospital, Ankara, Turkey.
Necati HancerliogullariMinistry of Health Ankara City Hospital, Ankara, Turkey.
Nafiye YilmazMinistry of Health Ankara City Hospital, Ankara, Turkey.
Yaprak Engin-UstunEtlik Zübeyde Hanim Women's Health Education and Research Hospital, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the predictive role of inflammatory hematological markers on treatment success in in vitro fertilization (IVF) patients.

methodsIn this study, we analyzed the data from the patients who admitted to our IVF center, and we recorded demographic characteristics, medical histories, laboratory biomarkers, cycle characteristics, and IVF outcomes from the patients' files. We assessed the value of white blood cell (WBC) counts, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), platelet/lymphocyte (PLR), mean platelet volume (MPV) and platelet distribution width (PDW) of the patients from their complete blood count. We compared these values in terms of predicting positive HCG test after embryo transfer (ET).

resultsThere were 132 patients, of which 63 (47.7%) were treated for male factor, 43 (32.6%) for unexplained infertility, 19 (14.4%) for diminished ovarian reserve, 5 (3.8%) for endometriosis and 2 (1.5%) for hypogonadotropic hypogonadism. After ovarian stimulation and oocyte retrieval, 115 patients underwent embryo transfer, and 28 patients had a positive HCG test (24.3%). The positive HCG group had a statistically lower PLR when compared to the HCG (-) group (p=0.02). In the ROC analysis, PLR was significant in predicting positive HCG (p=0.028). However, when we added other factors to the model, only age and MII oocyte count were successful in predicting pregnancy outcomes in a logistic regression analysis.

conclusionAccording our results, inflammatory hematological markers were not effective in predicting IVF success.

Indexed as

LymphocytesMean Platelet VolumeBiomarkersFemaleFertilization in VitroHumansMaleNeutrophilsPregnancyRetrospective StudiesBiomarkersinfertilityinflammatory hematologic markersin vitro fertilizationplatelet/lymphocyte ratio

Identifiers

PMID32759097
PMCPMC7863106

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.