Evidence map›Paper›PMID 32758526›Full record

ReviewJournal of structural biology2020

Insights into dental mineralization from three heritable mineralization disorders.

Michael B Chavez, Kaitrin Kramer, Emily Y Chu, Vivek Thumbigere-Math, Brian L Foster

Open access · greenAbstract readReview
In one paragraph

Review in Journal of structural biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Dental disease burden and management in children and young people with X-linked hypophosphataemia: a scoping review and service evaluation.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Dentoalveolar Alterations in an Adenine-Induced Chronic Kidney Disease Mouse Model.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Article
  13. Article
  14. Article
  15. Approach to Hypophosphatemic Rickets.The Journal of clinical endocrinology and metabolism · 2022
    Article
  16. Article
  17. Dentoalveolar Defects of Hypophosphatasia are Recapitulated in a Sheep Knock-In Model.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Article
  18. Review
  19. Effects of Active Vitamin D or FGF23 Antibody onJournal of dental research · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Michael B ChavezDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA.
Kaitrin KramerDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
Emily Y ChuNational Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
Vivek Thumbigere-MathDivision of Periodontology, University of Maryland School of Dentistry, Baltimore, MD, USA.
Brian L FosterDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, USA. Electronic address: foster.1004@osu.edu.
The Ohio State University · USNational Institutes of Health · USUniversity of Maryland, Baltimore · US

Funding

Comprehensive Training in Oral &Craniofacial SciencesT32DE014320 · NIDCR · OHIO STATE UNIVERSITY · PI SHERIDAN, JOHN F · 2001 to 2022
$10.2M
Duke University Program in Environmental HealthT32ES021432 · NIEHS · DUKE UNIVERSITY · PI Akhenaton-Andrew Dhafir Jones, Joel Newman Meyer · 2013 to 2026
$4.0M
Follow-up and Maintenance of the Newborn Epigenetics STudy (NEST) CohortR24ES028531 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOYO, CATHRINE, MURPHY, SUSAN KAY · 2018 to 2022
$1.9M
The Role of Interferon Regulatory Factor 8 (IRF8) in Periodontal DiseaseR00DE028439 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE · PI THUMBIGERE-MATH, VIVEK · 2018 to 2020
$747k
Role of tissue-nonspecific alkaline phosphatase in dentoalveolar development and diseaseR03DE028411 · NIDCR · OHIO STATE UNIVERSITY · PI FOSTER, BRIAN LEE · 2019 to 2020
$312k
Function of cementocytes in cellular cementum formation and resorptionR03DE028632 · NIDCR · OHIO STATE UNIVERSITY · PI FOSTER, BRIAN LEE · 2019 to 2020
$307k
NIDCR NIH HHS K99 DE028439NIDCR NIH HHS R00 DE028439NIDCR NIH HHS R03 DE028411NIDCR NIH HHS R03 DE028632NIDCR NIH HHS T32 DE014320NIEHS NIH HHS R24 ES028531NIEHS NIH HHS T32 ES021432
6 · The paper itself

Abstract

Teeth are comprised of three unique mineralized tissues, enamel, dentin, and cementum, that are susceptible to developmental defects similar to those affecting bone. X-linked hypophosphatemia (XLH), caused by PHEX mutations, leads to increased fibroblast growth factor 23 (FGF23)-driven hypophosphatemia and local extracellular matrix disturbances. Hypophosphatasia (HPP), caused by ALPL mutations, results in increased levels of inorganic pyrophosphate (PP

Indexed as

Alkaline PhosphataseAnimalsCalcification, PhysiologicExtracellular MatrixFamilial Hypophosphatemic RicketsFibroblast Growth Factor-23Fibroblast Growth FactorsHumansHypophosphatasiaToothVascular CalcificationAlkaline PhosphataseFGF23 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsCementumDentinEnamelHypophosphatemiaMineralized tissues

Identifiers

PMID32758526
PMCPMC7530110
OpenAlexW3047087029

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.