Evidence map›Paper›PMID 32758380›Full record

ArticleVaccine2020

Prevalence and characteristics of HPV vaccine hesitancy among parents of adolescents across the US.

Peter G Szilagyi, Christina S Albertin, Dennis Gurfinkel, Alison W Saville, Sitaram Vangala, John D Rice, Laura Helmkamp, Gregory D Zimet, Rebecca Valderrama, Abigail Breck and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 1 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 1 synthesis or guideline pooled it, 218 citations in OpenAlex.

  1. Pooled it
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  6. Centralized Reminder/Recall for Human Papillomavirus Vaccination: Findings From Two States-A Randomized Clinical Trial.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2021
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  15. Determinants of HPV vaccine hesitancy in South Asia: a systematic review.Clinical and experimental vaccine research · 2026
    Review
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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Peter G SzilagyiDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA. Electronic address: PSzilagyi@mednet.ucla.edu.
Christina S AlbertinDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA. Electronic address: Christina_Albertin@URMC.Rochester.edu.
Dennis GurfinkelAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA. Electronic address: Dennis.Gurfinkel@cuanschutz.edu.
Alison W SavilleAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA. Electronic address: Alison.saville@cuanschutz.edu.
Sitaram VangalaDepartment of Medicine, Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. Electronic address: Svangala@mednet.ucla.edu.
John D RiceAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA; Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA. Electronic address: John.Rice@cuanschutz.edu.
Laura HelmkampAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA. Electronic address: Laura.Helmkamp@cuanschutz.edu.
Gregory D ZimetDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: gzimet@iu.edu.
Rebecca ValderramaDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA.
Abigail BreckDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA. Electronic address: Abreck@mednet.ucla.edu.
Cynthia M RandDepartment of Pediatrics, University of Rochester, School of Medicine and Dentistry, Rochester, NY, USA. Electronic address: Cynthia_Rand@urmc.rochester.edu.
Sharon G HumistonDepartment of Pediatrics, Children's Mercy, Kansas City, MO, USA. Electronic address: sghumiston@cmh.edu.
Allison KempeAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA. Electronic address: Allison.kempe@childrenscolorado.org.
University of California, Los Angeles · USOutcomes Research Consortium · USChildren's Hospital Colorado · USChildren's Mercy Hospital · USColorado School of Public Health · USIndiana University School of MedicineUniversity of Rochester Medical Center · US

Funding

State Immunization Information Systems to Improve HPV Vaccination RatesR01CA187707 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KEMPE, ALLISON, SZILAGYI, PETER G · 2015 to 2018
$2.4M
NCI NIH HHS R01 CA187707
6 · The paper itself

Abstract

backgroundWhile many clinicians encounter parents or adolescents who refuse HPV vaccine, little is known about the prevalence of hesitancy for HPV vaccine nationally or its association with vaccination.

methodsIn April 2019, we surveyed families with adolescents 11-17 years using a national online panel (Knowledge Panel®) as the sampling frame. We assessed the prevalence of HPV vaccine hesitancy with the validated 9-item Vaccine Hesitancy Scale (VHS). We used multivariate analyses to assess demographic factors associated with HPV vaccine hesitancy. We also assessed practical barriers to receipt of HPV vaccine and the relationship between barriers and hesitancy. Finally, we evaluated the association between both HPV vaccine hesitancy and practical barriers on HPV vaccine receipt or refusal.

results2,177 parents out of 4,185 sampled (52%) completed the survey, 2,020 qualified (lived with adolescent). Using a VHS cut-off score > 3 out of 5 points, 23% of US parents were hesitant about HPV vaccine. Hesitancy was lower among those with Hispanic ethnicity. At least one out of five parents disagreed that the HPV vaccine is beneficial for their adolescent, that the vaccine is effective, protects against HPV-related cancers, or that they followed their adolescent's health-care provider's recommendation about the vaccine. Many were concerned about vaccine side effects and the novelty of the vaccine. Adolescents living with vaccine-hesitant parents were less than one-third as likely to have received the vaccine (RR = 0.29, 95% CI 0.24, 0.35) or completed the vaccine series (RR = 0.29, 95% CI 0.23, 0.36), and were 6-fold more likely to have refused the vaccine because of parental vaccine-related concerns (RR = 6.09, 95% CI = 5.26, 7.04). Most practical barriers were independently associated with vaccine receipt but not with vaccine refusal.

conclusionsHPV vaccine hesitancy is common nationally and strongly related to both under-vaccination and vaccine refusal.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesAdolescentHealth Knowledge, Attitudes, PracticeHumansParentsPatient Acceptance of Health CarePrevalenceVaccinationVaccination RefusalPapillomavirus VaccinesHPV vaccineVaccine hesitancy

Identifiers

PMID32758380
PMCPMC9495911
OpenAlexW3046511521

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.