ReviewInternational braz j urol : official journal of the Brazilian Society of Urology
The role of intra-abdominal pressure in human testicular migration.
Review in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- The effect of imaging evaluation on surgery for giant omphalocele: a case description.Quantitative imaging in medicine and surgery · 2025Article
- External pressure induces the dysfunction of spermatogonia via triggering the intrinsic pathway of apoptosis.Translational andrology and urology · 2024Article
- Testicular descent revisited: a micro-computed tomography study in fetal rats.Pediatric surgery international · 2023Article
- Investigation of a connection between abdominal wall defects and severity of the herniation in fetuses with gastroschisis and omphalocele.Scientific reports · 2021Article
- Translational research in testicular migration.International braz j urol : official journal of the Brazilian Society of UrologyArticle
- Editorial Comment: Prevalence, management and outcome of cryptorchidism associated with gastroschisis: A systematic review and meta-analysis.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis review aims to study the role of the abdominal wall in testicular migration process during the human fetal period. MATERIALS AND
methodsWe performed a descriptive review of the literature about the role of the abdominal wall in testicular migration during the human fetal period.
resultsThe rise in intra-abdominal pressure is a supporting factor for testicular migration. This process has two phases: the abdominal and the inguinal-scrotal stages. The passage of the testis through the inguinal canal occurs very quickly between 21 and 25 WPC. Bilateral cryptorchidism in Prune Belly syndrome is explained by the impaired contraction of the muscles of the abdominal wall; mechanical obstruction due to bladder distention and structural alteration of the inguinal canal, which hampers the passage of the testis during the inguinoscrotal stage of testicular migration. Abdominal wall defects as gastroschisis and omphaloceles are associated with undescended testes in around 30 to 40% of the cases.
conclusionsAbdominal pressure wound is an auxiliary force in testicular migration. Patients with abdominal wall defects are associated with undescendend testis in more than 30% of the cases probably due to mechanical factors; the Prune Belly Syndrome has anatomical changes in the anterior abdominal wall that hinder the increase of intra-abdominal pressure which could be the cause of cryptorchidism in this syndrome.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.