Evidence map›Paper›PMID 32758221›Full record

ArticleBMC veterinary research2020

First report and genetic characterization of bovine torovirus in diarrhoeic calves in China.

Zhihai Shi, Wenjia Wang, Chaoxi Chen, Xiaozhan Zhang, Jing Wang, Zhaoxue Xu, Yali Lan

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhihai ShiInstitute of Animal Husbandry and Veterinary Medicine, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, China.ORCID https://orcid.org/0000-0002-4083-5331
Wenjia WangCollege of Veterinary Medicine and Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou, 450046, Henan, China.ORCID https://orcid.org/0000-0002-3023-4698
Chaoxi ChenCollege of Life Science and Technology, Southwest University for Nationalities, Chengdu, 610041, Sichuan, China.
Xiaozhan ZhangCollege of Veterinary Medicine and Pharmaceutical Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou, 450046, Henan, China. xiaozhan063@163.com.ORCID https://orcid.org/0000-0002-0280-4964
Jing WangInstitute of Animal Husbandry and Veterinary Medicine, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, China.
Zhaoxue XuInstitute of Animal Husbandry and Veterinary Medicine, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, China.
Yali LanInstitute of Animal Husbandry and Veterinary Medicine, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, Henan, China. lanyali66@163.com.
Henan Academy of Agricultural Sciences · CNHenan University · CNSouthwest Minzu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronaviruses are notorious pathogens that cause diarrheic and respiratory diseases in humans and animals. Although the epidemiology and pathogenicity of coronaviruses have gained substantial attention, little is known about bovine coronavirus in cattle, which possesses a close relationship with human coronavirus. Bovine torovirus (BToV) is a newly identified relevant pathogen associated with cattle diarrhoea and respiratory diseases, and its epidemiology in the Chinese cattle industry remains unknown.

resultsIn this study, a total of 461 diarrhoeic faecal samples were collected from 38 different farms in three intensive cattle farming regions and analysed. Our results demonstrated that BToV is present in China, with a low prevalence rate of 1.74% (8/461). The full-length spike genes were further cloned from eight clinical samples (five farms in Henan Province). Phylogenetic analysis showed that two different subclades of BToV strains are circulating in China. Meanwhile, the three BToV strains identified from dairy calves, 18,307, 2YY and 5YY, all contained the amino acid variants R614Q, I801T, N841S and Q885E.

conclusionsThis is the first report to confirm the presence of BToV in beef and dairy calves in China with diarrhea, which extend our understanding of the epidemiology of BToVs worldwide.

Indexed as

AnimalsCattleCattle DiseasesChinaDiarrheaFecesPhylogenyRNA, ViralSequence Analysis, DNATorovirusTorovirus InfectionsViral ProteinsRNA, ViralViral ProteinsBeefBovine torovirusCalf diarrhoeaChinaDairyPhylogenetic analysis

Identifiers

PMID32758221
PMCPMC7404080
OpenAlexW3047243304

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.