Evidence map›Paper›PMID 32758187›Full record

ArticleBMC ophthalmology2020

Plasma Ephrin-A1 level in a cohort of diabetic retinopathy patients.

Danna Mao, Ying Hu, Qi Bao, Kewei Wu, Yaoding Zheng, Yukun Yang, Bo Lei, Ying Jiang

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Eph Receptors and Ephrins in Retinal Diseases.International journal of molecular sciences · 2021
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Danna MaoDepartment of Ophthalmology, Medical community of Fenghua Hospital of Traditional Chinese Medicine, 22 Zhong Shan Road, Feng Hua District, NingBo, 315500, ZheJiang, China.
Ying HuDepartment of Ophthalmology, Medical community of Fenghua Hospital of Traditional Chinese Medicine, 22 Zhong Shan Road, Feng Hua District, NingBo, 315500, ZheJiang, China.
Qi BaoDepartment of Clinical Laboratory, Medical community of Fenghua Hospital of Traditional Chinese Medicine, Ningbo, Zhejiang, China.
Kewei WuDepartment of Ophthalmology, Medical community of Fenghua Hospital of Traditional Chinese Medicine, 22 Zhong Shan Road, Feng Hua District, NingBo, 315500, ZheJiang, China.
Yaoding ZhengDepartment of Ophthalmology, Medical community of Fenghua Hospital of Traditional Chinese Medicine, 22 Zhong Shan Road, Feng Hua District, NingBo, 315500, ZheJiang, China.
Yukun YangDepartment of Ophthalmology, Medical community of Fenghua Hospital of Traditional Chinese Medicine, 22 Zhong Shan Road, Feng Hua District, NingBo, 315500, ZheJiang, China.
Bo LeiPeople's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Henan Eye Institute, Henan Eye Institute, 7# Weiwu Road, Zhengzhou, 450003, Henan, China. bolei99@126.com.
Ying JiangDepartment of Ophthalmology, Medical community of Fenghua Hospital of Traditional Chinese Medicine, 22 Zhong Shan Road, Feng Hua District, NingBo, 315500, ZheJiang, China. gateways@126.com.
Henan Provincial Eye Hospital · CN

Funding

Fenghua District Science and Technology Bureau 20173604
6 · The paper itself

Abstract

backgroundTo determine plasma ephrin-A1 and VEGF

methodsPlasma ephrin-A1 and VEGF

resultsEphrin-A1 expression could be detected in human plasma with an average of 1.52 ± 0.43 (mean ± SEM) ng/ml. In DR subjects, the plasma ephrin-A1concentration was 3.63 ± 4.63 ng/ml, which was significantly higher than that of the other two groups (non-DM: 0.27 ± 0.13 ng/ml, DM: 0.35 ± 0.34 ng/ml). The expression of VEGF

conclusionsPlasma ephrin-A1 was highly expressed in patients with diabetic retinopathy, and there was no difference of plasma VEGF

Indexed as

Diabetes Mellitus, Type 2Diabetic RetinopathyBiomarkersCohort StudiesEphrin-A1HumansBiomarkersEFNA1 protein, humanEphrin-A1Diabetic retinopathyELISAEphrin-A1PlasmaVEGF165

Identifiers

PMID32758187
PMCPMC7404912
OpenAlexW3047002121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.