Evidence map›Paper›PMID 32757714›Full record

ArticleInternational journal of STD & AIDS2020

Hypothermia - an unusual initial presentation of human immunodeficiency virus infection.

S J Simpson, A Ratnappuli, M E Porte, H McGann, C J Lacey

Open access · hybridAbstract readCase Reports
In one paragraph

Article in International journal of STD & AIDS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

S J SimpsonHull York Medical School, University of York, York, UK.
A RatnappuliHull York Medical School, University of York, York, UK.
M E PorteRadiology, York Teaching Hospital, York, UK.
H McGannInfectious Diseases, St James University Hospital, Leeds, UK.
C J LaceyHull York Medical School, University of York, York, UK.ORCID 0000-0001-9250-2638
University of York · GBSt James's University Hospital · GBYork Teaching Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an unusual case of human immunodeficiency virus (HIV) infection initially presenting with hypothermia and bradycardia associated with an HIV encephalitis. Searches reveal only five reported cases of spontaneous episodic hypothermia in the context of HIV infection. In our case, magnetic resonance imaging revealed the presence of a persistent cavum septum pellucidum (CSP), an anatomical and functional neuro-developmental abnormality, as well as changes compatible with an HIV encephalitis. Episodic hypothermia can occur in association with agenesis of the corpus callosum, known as Shapiro's syndrome, and the presence of a persistent CSP in our case suggests it may have contributed to the clinical presentation.

Indexed as

Antiretroviral Therapy, Highly ActiveAdultAIDS Dementia ComplexCD4 Lymphocyte CountHIV InfectionsHumansHypothermiaImmunoglobulin GMagnetic Resonance ImagingMalePancytopeniaTreatment OutcomeViral LoadImmunoglobulin GencephalopathyHIVhypothermia

Identifiers

PMID32757714
PMCPMC7549277
OpenAlexW3047643152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.