Evidence map›Paper›PMID 32757690›Full record

ArticleAutophagy2021

ATM loss disrupts the autophagy-lysosomal pathway.

Aifang Cheng, Kai-Hei Tse, Hei-Man Chow, Yunqiao Gan, Xuan Song, Fulin Ma, Yi Xuan Yvonne Qian, Weiyi She, Karl Herrup

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Aifang ChengDivision of Life Science, The Hong Kong University of Science and Technology, Hong Kong.ORCID 0000-0002-5022-418X
Kai-Hei TseDivision of Life Science, The Hong Kong University of Science and Technology, Hong Kong.ORCID 0000-0001-7287-3984
Hei-Man ChowSchool of Life Sciences, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0003-1203-2096
Yunqiao GanDivision of Life Science, The Hong Kong University of Science and Technology, Hong Kong.ORCID 0000-0002-6391-4286
Xuan SongDivision of Life Science, The Hong Kong University of Science and Technology, Hong Kong.ORCID 0000-0002-2031-3966
Fulin MaDivision of Life Science, The Hong Kong University of Science and Technology, Hong Kong.ORCID 0000-0002-0333-3180
Yi Xuan Yvonne QianLi Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.
Weiyi SheDepartment of Ocean Science, The Hong Kong University of Science and Technology, Hong Kong.
Karl HerrupDivision of Life Science, The Hong Kong University of Science and Technology, Hong Kong.ORCID 0000-0001-7786-5844
Hong Kong University of Science and Technology · HKChinese University of Hong Kong · HKHong Kong Polytechnic University · HKUniversity of Hong Kong · HKUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ATM (ataxia telangiectasia mutated) protein is found associated with multiple organelles including synaptic vesicles, endosomes and lysosomes, often in cooperation with ATR (ataxia telangiectasia and Rad3 related). Mutation of the

Indexed as

Adaptor Proteins, Signal TransducingAnimalsAtaxia Telangiectasia Mutated ProteinsAutophagosomesAutophagyHumansLysosomesMicePhagocytosisUbiquitinAdaptor Proteins, Signal TransducingAtaxia Telangiectasia Mutated ProteinsATM protein, humanAtm protein, mouseUbiquitinAtaxia-telangiectasiaautophagylysosomeneurodegenerationprotein degradationSLC2A4/GLUT4trafficking

Identifiers

PMID32757690
PMCPMC8386711
OpenAlexW3047487122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.