Evidence map›Paper›PMID 32757659›Full record

ReviewCirculation. Cardiovascular interventions2020

Percutaneous Interventions for Secondary Mitral Regurgitation.

Mahboob Ali, Satya S Shreenivas, David N Pratt, Donald R Lynch, Dean J Kereiakes

Abstract readReview
In one paragraph

Review in Circulation. Cardiovascular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Curved Bistable Origami-Inspired Flexible Transcatheter Mitral Valve Clamping.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Device Therapy in Chronic Heart Failure: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2021
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahboob AliUniversity of Cincinnati, OH (M.A., D.N.P., D.R.L.).
Satya S ShreenivasThe Christ Hospital, Cincinnati, OH (S.S.S., D.J.K.).
David N PrattUniversity of Cincinnati, OH (M.A., D.N.P., D.R.L.).
Donald R LynchUniversity of Cincinnati, OH (M.A., D.N.P., D.R.L.).
Dean J KereiakesThe Christ Hospital, Cincinnati, OH (S.S.S., D.J.K.).

Funding

Platelets and Hemostatic Factors as Facilitators of the Inflammatory Response Following Transcatheter Aortic Valve ReplacementK23HL151872 · NHLBI · UNIVERSITY OF CINCINNATI · PI LYNCH, DONALD RAY · 2020 to 2024
$974k
NHLBI NIH HHS K23 HL151872
6 · The paper itself

Abstract

Mitral regurgitation is frequently associated with ventricular dysfunction and carries a high mortality. Guideline-directed medical therapy, surgical mitral valve repair or replacement, and, in the setting of advanced heart failure, heart transplant and left ventricular assist devices have been the mainstay of treatment. However, rapid advancement in the field has resulted in approval of edge-to-edge mitral valve repair with the MitraClip, and there are several novel catheter-based percutaneous options in clinical trials. Percutaneous options, while promising, must be deployed in patients who are most likely to benefit, and thus, understanding the pathophysiology of specific subgroups of patients with functional mitral regurgitation (eg, disproportionate versus proportionate mitral regurgitation) is key to the success of new devices. We review the pathophysiology, percutaneous therapeutic treatment options, and ongoing clinical trials for functional mitral regurgitation.

Indexed as

Heart Valve Prosthesis ImplantationAgedCardiac CatheterizationClinical Decision-MakingFemaleHeart Valve ProsthesisHemodynamicsHumansMaleMitral ValveMitral Valve InsufficiencyRecovery of FunctionRisk AssessmentRisk FactorsTreatment OutcomeVentricular Function, Leftmitral regurgitationmitral valvemitral valve insufficiencypercutaneous mitral valve repairpercutaneous mitral valve replacementtranscatheter mitral valve replacement

Identifiers

PMID32757659
PMCPMC8207332

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.