Evidence map›Paper›PMID 32757599›Full record

ReviewJournal of abnormal psychology2020

Computational models of drug use and addiction: A review.

Jessica A Mollick, Hedy Kober

Open access · greenAbstract readReview
In one paragraph

Review in Journal of abnormal psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 61 citations in OpenAlex.

  1. Trial
  2. Article
  3. Rapid and reliable computational markers of decision-making for predicting daily smoking behavior and smoking cessation treatment outcomes.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Explaining "U-shaped" distributions of population substance use with a simple computational approach.Journal of artificial societies and social simulation : JASSS · 2025
    Article
  9. Article
  10. Neuroimaging Biomarkers in Addiction.medRxiv : the preprint server for health sciences · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Neuromarkers in addiction: definitions, development strategies, and recent advances.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Listening to the Data: Computational Approaches to Addiction and Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jessica A MollickClinical and Affective Neuroscience Lab, Department of Psychiatry, Yale University.
Hedy KoberClinical and Affective Neuroscience Lab, Department of Psychiatry, Yale University.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Regulation of Craving: Clinical Trial and Neural MechanismsR01AA029137 · NIAAA · YALE UNIVERSITY · PI KOBER, HEDY · 2021 to 2025
$3.4M
Regulation of Craving Under Stress: Neural Mechanisms and Novel ModelR01DA042911 · NIDA · YALE UNIVERSITY · PI KOBER, HEDY · 2017 to 2021
$3.2M
Meta-Analysis and Machine Learning: Towards Neuromarkers of Craving and RelapseR01DA043690 · NIDA · YALE UNIVERSITY · PI KOBER, HEDY · 2017 to 2019
$1.3M
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS R01 AA029137NIDA NIH HHS R01 DA042911NIDA NIH HHS R01 DA043690
6 · The paper itself

Abstract

In this brief review, we describe current computational models of drug-use and addiction that fall into 2 broad categories: mathematically based models that rely on computational theories, and brain-based models that link computations to brain areas or circuits. Across categories, many are models of learning and decision-making, which may be compromised in addiction. Several mathematical models take predictive coding approaches, focusing on Bayesian prediction error. Other models focus on learning processes and (traditional) prediction error. Brain-based models have incorporated prefrontal cortex, basal ganglia, and the dopamine system, based on the effects of drugs on dopamine, motivation, and executive control circuits. Several models specifically describe how behavioral control may transition from habitual to goal-directed systems, consistent with computational accounts of compromised "model-based" control. Some brain-based models have linked this to the transition of behavioral control from ventral to dorsal striatum. Overall, we propose that while computational models capture some aspects of addiction and have advanced our thinking, most have focused on the effects of drug use rather than addiction per se, most have not been tested on and/or supported by human data, and few capture multiple stages and symptoms of addiction. We conclude by suggesting a path forward for computational models of addiction. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Indexed as

Computer SimulationModels, NeurologicalBehavior, AddictiveBrainHumansLearningMotivationSubstance-Related Disorders

Identifiers

PMID32757599
PMCPMC7416739
OpenAlexW3047771476

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.