Evidence map›Paper›PMID 32757404›Full record

SynthesisEuropean journal of neurology2020

Guillain-Barré syndrome associated with SARS-CoV-2 infection. A systematic review.

P De Sanctis, P E Doneddu, L Viganò, C Selmi, E Nobile-Orazio

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in European journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Miller Fisher syndrome associated with COVID-19: an up-to-date systematic review.Environmental science and pollution research international · 2021
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Neurologic and Neuromuscular Sequelae of COVID-19.Physical medicine and rehabilitation clinics of North America · 2023
    Review
  10. Immediate and contributory causes of death in patients hospitalized with COVID-19.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Neuro-COVID-19.Clinical & experimental neuroimmunology · 2022
    Review
  16. Guillain-Barré syndrome following different COVID-19 vaccines: a case series.The Egyptian journal of neurology, psychiatry and neurosurgery · 2022
    Article
  17. Is there a difference between GBS triggered by COVID-19 and those of other origins?The Egyptian journal of neurology, psychiatry and neurosurgery · 2022
    Article
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

P De SanctisDepartment of Neurosurgery, Humanitas Clinical and Research Institute - IRCCS, Rozzano (MI), Italy.
P E DonedduDepartment of Neurology, Neuromuscular and Neuroimmunology Service, Humanitas Clinical and Research Institute - IRCCS, Rozzano (MI), Italy.ORCID 0000-0003-4203-6792
L ViganòDepartment of General Surgery, Humanitas Clinical and Research Institute - IRCCS, Rozzano (MI), Italy.
C SelmiDepartment of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Institute - IRCCS, Rozzano (MI), Italy.
E Nobile-OrazioDepartment of Neurology, Neuromuscular and Neuroimmunology Service, Humanitas Clinical and Research Institute - IRCCS, Rozzano (MI), Italy.ORCID 0000-0003-2624-8138
Humanitas University · ITAmerican Institute of Biological Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guillain-Barré syndrome (GBS) incidence can increase during outbreaks of infectious illnesses. A few cases of GBS associated with coronavirus disease 2019 (COVID-19) infection have been reported. The aim was to identify specific clinical features of GBS associated with COVID-19. PubMed, Embase and Cochrane were searched from 1 November 2019 to 17 May 2020 and included all papers with full text in English, Spanish, French or Italian, reporting original data of patients with GBS and COVID-19. Data were extracted according to a predefined protocol. A total of 18 patients reported in 14 papers were included in this review. All the patients were symptomatic for COVID-19, with cough and fever as the most frequently reported symptoms. The interval between the onset of symptoms of COVID-19 and the first symptoms of GBS ranged from -8 to 24 days (mean 9 days; median 10 days). Most of the patients had a typical GBS clinical form predominantly with a demyelinating electrophysiological subtype. Mechanical ventilation was necessary in eight (44%) patients. Two (11%) patients died. Published cases of GBS associated with COVID-19 report a sensorimotor, predominantly demyelinating GBS with a typical clinical presentation. Clinical features and disease course seem similar to those observed in GBS related to other etiologies. These results should be interpreted with caution since only 18 cases have been heterogeneously reported so far.

Indexed as

COVID-19Demyelinating DiseasesGuillain-Barre SyndromeHumanscoronavirus 2019 diseaseCOVID-19Guillain-Barré syndromeneuropathySARS-CoV-2

Identifiers

PMID32757404
PMCPMC7436512
OpenAlexW3047278485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.