Evidence map›Paper›PMID 32757314›Full record

ArticleCancer2020

Choice of local therapy for young women with early-stage breast cancer who have young-aged children.

I-Wen Pan, Tina W F Yen, Jinhai Huo, Cheng Chen, Benjamin D Smith, Ya-Chen Tina Shih

Open access · greenAbstract read
In one paragraph

Article in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

I-Wen PanDepartment of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-2781-2629
Tina W F YenDepartment of Surgery, Medical College of Wisconsin, Wauwatosa, Wisconsin.ORCID 0000-0001-7210-4333
Jinhai HuoDepartment of Health Services Research, Management and Policy, College of Public Health and Health Professions, University of Florida, Gainesville, Florida.
Cheng ChenDepartment of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, Florida.
Benjamin D SmithDepartment of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Ya-Chen Tina ShihDepartment of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0001-7290-3864
The University of Texas MD Anderson Cancer Center · USFlorida Department of Health · USMedical College of Wisconsin · USUniversity of Florida · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Technology Diffusion in Cancer: Geographic Variations, Facilitators, Outcomes, and CostsR01CA207216 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHIH, YA-CHEN TINA · 2016 to 2020
$1.6M
NCI NIH HHS CA016672NCI NIH HHS CA207216NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA207216
6 · The paper itself

Abstract

backgroundDecision making regarding the initial treatment of women with breast cancer is complicated. In the current study, the authors examined the relationship between treatment choices and their children's ages among young women with early-stage breast cancer.

methodsUsing the MarketScan Commercial Claims and Encounters database, the authors identified women aged 20 to 50 years who underwent lumpectomy or mastectomy for early-stage breast cancer between 2008 and 2014. Predictors of compliance with radiotherapy after undergoing lumpectomy and of undergoing mastectomy were determined using multinomial logistic regression. The authors conducted sensitivity analyses to explore the impact of the number of young-aged children and a reduction in the sample size in 2014 due to the attrition of health plans contributing to MarketScan.

resultsA total of 21,052 women were included in the current analysis. Among women with at least 1 child aged <7 years, the adjusted rate of lumpectomy was 59.9%; approximately 22% of these women did not receive radiotherapy. Compared with women undergoing lumpectomy plus radiotherapy, women with at least 1 child aged <7 years or aged 7 to 12 years were 25% and 16%, respectively, more likely to undergo lumpectomy alone compared with women with no children aged <18 years (P = .002 and P = .012, respectively) and 64% and 37%, respectively, more likely to undergo mastectomy (P < .001).

conclusionsAmong privately insured women with breast cancer, having young children was found to be strongly associated with the omission of postlumpectomy radiotherapy or undergoing mastectomy. Having >1 young-aged child further amplified these associations. The findings of the current study suggested that caring for young children may present unique challenges to young women with breast cancer.

Indexed as

AdultBreast NeoplasmsFemaleHumansMiddle AgedNeoplasm StagingYoung Adultbreast cancerchildren's agelumpectomymastectomytreatment choices

Identifiers

PMID32757314
PMCPMC9109152
OpenAlexW3047545628

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.