Evidence map›Paper›PMID 32757288›Full record

ReviewMicrobiology and immunology2020

Animal infection models using non-mammals.

Chikara Kaito, Kanade Murakami, Lina Imai, Kazuyuki Furuta

Abstract readReview
In one paragraph

Review in Microbiology and immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Article
  3. Establishment ofFrontiers in microbiology · 2026
    Article
  4. Silkworm Infection Model for Evaluating Bacterial Virulence Genes.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Frontiers in microbiology · 2026
    Article
  6. Combination effect of meropenem and antifungals againstJournal of medical microbiology · 2025
    Article
  7. Article
  8. Infection and immunity · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Frontiers in tuberculosis · 2025
    Review
  13. Effect ofNAM journal · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chikara KaitoGraduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.ORCID http://orcid.org/0000-0002-2895-3386
Kanade MurakamiGraduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Lina ImaiGraduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Kazuyuki FurutaGraduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

Funding

Ichiro Kanehara FoundationJSPS Grants-in-Aid for Scientific Research 19H03466JSPS Grants-in-Aid for Scientific Research 19K22523Takeda Science Foundation
6 · The paper itself

Abstract

The use of non-human animal models for infection experiments is important for investigating the infectious processes of human pathogenic bacteria at the molecular level. Mammals, such as mice and rabbits, are also utilized as animal infection models, but large numbers of animals are needed for these experiments, which is costly, and fraught with ethical issues. Various non-mammalian animal infection models have been used to investigate the molecular mechanisms of various human pathogenic bacteria, including Staphylococcus aureus, Streptococcus pyogenes, and Pseudomonas aeruginosa. This review discusses the desirable characteristics of non-mammalian infection models and describes recent non-mammalian infection models that utilize Caenorhabditis elegans, silkworm, fruit fly, zebrafish, two-spotted cricket, hornworm, and waxworm.

Indexed as

Disease Models, AnimalAnimalsBacteriaBacterial InfectionsBombyxCaenorhabditis elegansDrosophila melanogasterGryllidaeHumansLarvaManducaMothsZebrafishinfection modelnon-mammalspathogenic bacteria

Identifiers

PMID32757288
PMCPMC7590188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.