ArticleEuropean radiology2021
Accuracy, agreement, and reliability of DECT-derived vBMD measurements: an initial ex vivo study.
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Volumetric Bone Mineral Density Assessed by Dual-Energy CT Predicts Bone Strength Suitability for Cementless Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2025Article
- Effects of different combinations of noise index and preset adaptive statistical iterative reconstruction Veo on the accuracy and image quality of bone mineral density measurements using fast kilovolt-switching dual-energy computed tomography: a phantom study.Quantitative imaging in medicine and surgery · 2025Article
- The influence of proliferative tissue on Hounsfield unit and its correlation with BMD in middle-aged and elderly patients with lumbar degenerative diseases.Journal of orthopaedic surgery and research · 2024Article
- Quantification of bone quality and distribution of the proximal humerus with dual-energy computed tomography.Quantitative imaging in medicine and surgery · 2023Article
- Diagnostic accuracy of quantitative dual-energy CT-based volumetric bone mineral density assessment for the prediction of osteoporosis-associated fractures.European radiology · 2022Article
- Accuracy and precision of volumetric bone mineral density assessment using dual-source dual-energy versus quantitative CT: a phantom study.European radiology experimental · 2021Article
- Computed tomography-based opportunistic osteoporosis assessment: a comparison of two software applications for lumbar vertebral volumetric bone mineral density measurements.Quantitative imaging in medicine and surgery · 2021Article
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9 authors.
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Abstract
objectivesTo assess the agreement and reliability of DECT (dual-energy CT)-derived vBMD (volumetric bone mineral density) measurements from excised human femoral heads and to compare DECT-derived BMD with that measured by DXA (dual-energy X-ray absorptiometry) and QCT (quantitative CT) to determine its accuracy.
methodsTwenty patients that underwent total hip arthroplasty were enrolled to this study. Femoral heads were excised to rectangles without cortical bones for scanning. A dual-source DECT scanner generated images under 80/Sn140 kVp and 100/Sn140 kVp scanning conditions. Specimens were subsequently scanned by QCT and DXA to produce QCT-derived vBMD (mg/cm
resultsHigher DECT-derived vBMD and BMM were found under 80/Sn140 and 100/Sn140 kVp compared with those for QCT and DXA (p = 0.005). DECT-derived vBMD was highly correlated with QCT-derived vBMD (r = 0.961 ~ 0.993, p < 0.05). Similarly, DECT-derived BMM was strongly correlated with DXA-derived BMM (r = 0.927 ~ 0.943, p < 0.05). Agreement of the inter- and intra-observation of DECT-derived vBMD was excellent. Linear regression was carried out to calibrate DECT-derived vBMD of 80/Sn140 kVp (14 + 0.7 × DECT-derived vBMD) and 100/Sn140 kVp (74 + 0.4 × DECT-derived vBMD) with the reference of QCT-derived vBMD. After calibration, excellent agreement was found for vBMD and BMM within various imaging modalities.
conclusionsOur study showed that DECT-derived vBMD exhibited high agreement and reliability features, and after calibration, it also displayed a high degree of accuracy. However, in vivo studies are needed to extend its potential utility in clinical settings. KEY POINTS: • Measurements of DECT-derived vBMD had high intra- and inter-observer agreement and reliability. • Measurements of DECT-derived vBMD and BMM had a high correlation with those derived from QCT and DXA. • DECT-derived vBMD and BMM were accurate after calibration compared with QCT and DXA.
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