ArticleAmerican journal of clinical pathology2020
Peripheral Blood Examination Findings in SARS-CoV-2 Infection.
Article in American journal of clinical pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 59 citations in OpenAlex.
- NET-like Events on Peripheral Blood Smears at Admission: Association with Disease Severity and Systemic Inflammation in Hospitalized COVID-19 Patients.Medicina (Kaunas, Lithuania) · 2026Article
- Review
- MDS-Type Morphologic Abnormalities of Peripheral Blood Granulocytes in Symptomatic COVID-19 Patients.International journal of hematology-oncology and stem cell research · 2024Article
- Morphological Clues of Acute Monocytic Leukemia in COVID-19-Induced Transient Leukoerythroblastic Reaction with Monocytosis.Hematology reports · 2024Article
- Morphological abnormalities of leukocytes in SARS-CoV-2 infection.African health sciences · 2023Article
- A Review of Hematological Complications and Treatment in COVID-19.Hematology reports · 2023Review
- Hematopathology of Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Coronavirus Disease-19.Surgical pathology clinics · 2023Review
- Hematocytological Clues of Peripheral Blood in Different Clinical Presentations of COVID-19.Iranian journal of pathology · 2023Article
- Preliminary Study of sCD14 and sCD163 as Predictors of Disease Severity and ICU Admission in COVID-19: Relation to Hematological Parameters, Blood Morphological Changes and Inflammatory Biomarkers.Mediterranean journal of hematology and infectious diseases · 2023Article
- Young Woman with Unexplained Neutropenia and Neutrophils with Bilobed Nuclei: Marrow Findings.Case reports in hematology · 2023Article
- Normoblastemia in COVID-19 patients is associated with more severe disease and adverse outcome.International journal of clinical and experimental pathology · 2023Article
- SARS-CoV-2 infection of companion animals in Egypt and its risk of spillover.Veterinary medicine and science · 2023Article
- A multiple instance learning approach for detecting COVID-19 in peripheral blood smears.PLOS digital health · 2022Article
- Laboratory medicine in pandemic of COVID-19.Biochemia medica · 2022Article
- Haematological Traits in Symptomatic and Asymptomatic COVID-19 Positive Patients for Predicting Severity and Hospitalization.Journal of blood medicine · 2022Article
- Hematological changes associated with COVID-19 infection.Journal of clinical laboratory analysis · 2022Review
- Coagulation Studies Are Not Predictive of Hematological Complications of COVID-19 Infection.TH open : companion journal to thrombosis and haemostasis · 2022Article
- SARS-CoV-2 Immunization Orchestrates the Amplification of IFNγ-Producing T Cell and NK Cell Persistence.Frontiers in immunology · 2022Article
- Red Blood Cell Morphologic Abnormalities in Patients Hospitalized for COVID-19.Frontiers in physiology · 2022Article
- Peripheral blood cell anomalies in COVID-19 patients in the United Arab Emirates: A single-centered study.Frontiers in medicine · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPeripheral blood abnormalities in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been fully elucidated. We report qualitative and quantitative peripheral blood findings in coronavirus disease 2019 (COVID-19) patients and compare them with a control group.
methodsWe reviewed electronic medical records, complete blood counts, peripheral blood smears, and flow cytometry data in 12 patients with SARS-CoV-2. These were compared with 10 control patients with symptoms suspicious for SARS-CoV-2 but who tested negative.
resultsNo significant differences were noted in blood counts, except that absolute lymphopenia was present frequently in the control group (P < .05). Acquired Pelger-Huët anomaly (APHA) was noted in all COVID-19 cases, in most cases affecting over 5% of granulocytes. This contrasted with APHA in only 50% of control cases, affecting fewer than 5% of granulocytes in all cases (P < .05). Monolobate neutrophils were exclusive to COVID-19 cases. COVID-19 patients had greater frequency of plasmacytoid lymphocytes (P < .05). Flow cytometry data revealed absolute CD3+ T-cell count reduction in 6 of 7 patients; all of them required mechanical ventilation.
conclusionsLymphopenia was infrequent in our COVID-19 cohort; however, flow cytometric analysis revealed absolute T-cell count reduction in most cases. COVID-19 cases had significant APHA with monolobate neutrophils and plasmacytoid lymphocytes as compared to controls.
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