ArticleArquivos brasileiros de oftalmologia2020
Effects of pupillary dilation on ocular optical biometry outcomes in pediatric patients.
Article in Arquivos brasileiros de oftalmologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Effect of pupillary dilation on ocular biometry and intraocular lens power calculation: prospective cohort study.Journal of cataract and refractive surgery · 2026Article
- Effect of pupil dilation on spherical and toric IOL calculations using a swept source OCT ocular biometer.International ophthalmology · 2026Observational
- Effect of pharmacological pupil changes on intraocular lens power calculation: a systematic review and Meta-analysis.International journal of ophthalmology · 2025Article
- Effect of 3% diquafosol sodium eye drops on the prediction of intraocular lens power in predisposition to dry eye patients scheduled for cataract surgery: a prospective, observational study.Frontiers in medicine · 2025Article
- The accuracy of using vergence formula to screen myopia in children: a cross-sectional study.Frontiers in medicine · 2023Article
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Authors and funding
1 author at 1 institution in 1 country.
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Abstract
purposePharmacological pupillary dilation is performed in comprehensive ophthalmological examinations and before biometric measurements. So far, there is no consensus regarding its impact on biometric measurements. This study's aim was to investigate the effects of pharmacological pupillary dilation on ocular biometric measurements in healthy children.
methodsThis was a prospective, observational, non-randomized study of children (4-18 years of age) who were admitted for routine ophthalmological examination. Biometric measurements were performed, using a non-contact optical biometry device, both before and after pharmacological pupillary dilation with cyclopentolate hydrochloride. Intraocular lens power calculations were performed using Hill-RBF, Barrett, Olsen, Sanders-Retzlaff-Kraff/Theoretical, Holladay, and Hoffer Q formulas. Descriptive statistical analyses were also performed. The Wilcoxon signed-rank test was used to compare measurements before and after pharmacological pupillary dilation. Relationships between variables were analyzed using the Spearman-Brown rank correlation coefficient.
resultsThe study included 116 eyes of 58 children (mean age, 8.4 ± 0.32 years; 34 girls). Significant changes were observed after pupillary dilation, compared with before pupillary dilation, in terms of anterior chamber depth, aqueous depth, and central corneal and lens thicknesses. No significant change was observed in axial length. Intraocular lens power calculations revealed no significant changes after pupillary dilation in most formulas except for the Olsen formula. The intraocular lens power was significantly inversely correlated with axial length and anterior chamber depth.
conclusionsPharmacological pupillary dilation in children appeared to have no impact on axial length and intraocular lens power, but caused a significant increase in anterior chamber depth. The difference in anterior chamber depth measurements before and after pupillary dilation could be related to the optical biometry device model used. These outcomes should be considered in intraocular lens power calculations performed using anterior chamber depth parameters.
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