Evidence map›Paper›PMID 32756529›Full record

ArticleJournal of clinical medicine2020

Survival in Patients with Neuroendocrine Tumours of the Small Intestine: Nomogram Validation and Predictors of Survival.

Sonja Levy, Linde M van Veenendaal, Catharina M Korse, Emilie C H Breekveldt, Wieke H M Verbeek, Menno R Vriens, Koert F D Kuhlmann, José G van den Berg, Gerlof D Valk, Margot E T Tesselaar

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sonja LevyDepartment of Medical Oncology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.
Linde M van VeenendaalDepartment of Medical Oncology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.
Catharina M KorseDepartment of Clinical Chemistry, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.
Emilie C H BreekveldtDepartment of Medical Oncology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.
Wieke H M VerbeekDepartment of Gastroenterology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.
Menno R VriensDepartment of Endocrine Surgical Oncology, University Medical Centre Utrecht, 3584CX Utrecht, The Netherlands.
Koert F D KuhlmannDepartment of Surgical Oncology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.
José G van den BergDepartment of Pathology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.
Gerlof D ValkDepartment of Endocrine Oncology, University Medical Centre Utrecht, 3584CX Utrecht, the Netherlands.
Margot E T TesselaarDepartment of Medical Oncology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.

Funding

IPSEN unrestricted grant
6 · The paper itself

Abstract

Neuroendocrine tumours of the small intestine (SI-NETs) are rare and heterogeneous. There is an unmet need for prognostication of disease course and to aid treatment strategies. A previously developed nomogram based on clinical and tumour characteristics aims to predict disease-specific survival (DSS) in patients with a SI-NET. We aimed to validate the nomogram and identify predictors of survival. Four hundred patients with a grade 1 or 2 SI-NET were included, between January 2000 and June 2016. Predicted 5- and 10-year survival was compared to actual DSS. Multivariable analysis identified predictors for actual DSS. We found that in low-, medium- and high-risk groups 5-year nomogram DSS vs. actual DSS was 0.86 vs. 0.82 (

Indexed as

Neuroendocrine tumoursnomogramprediction modelprognosissmall-intestine

Identifiers

PMID32756529
PMCPMC7464451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.