Evidence map›Paper›PMID 32756499›Full record

ArticleCancers2020

Germline Genetic Findings Which May Impact Therapeutic Decisions in Families with a Presumed Predisposition for Hereditary Breast and Ovarian Cancer.

Carolina Velázquez, De Leeneer K, Eva M Esteban-Cardeñosa, Francisco Avila Cobos, Enrique Lastra, Luis E Abella, Virginia de la Cruz, Carmen D Lobatón, Kathleen B Claes, Mercedes Durán and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. GermlineJournal of personalized medicine · 2024
    Article
  5. ATM c.7570G>C is a high-risk allele for breast cancer.International journal of cancer · 2023
    Article
  6. Article
  7. Cancers · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Carolina VelázquezCancer Genetics Group, Instituto de Biología y Genética Molecular (UVa-CSIC), 47003 Valladolid, Spain.ORCID 0000-0003-2477-8338
De Leeneer KCenter for Medical Genetics, Ghent University Hospital, and Cancer Research Institute Ghent (CRIG), Ghent University, 9000 Ghent, Belgium.
Eva M Esteban-CardeñosaCancer Genetics Group, Instituto de Biología y Genética Molecular (UVa-CSIC), 47003 Valladolid, Spain.
Francisco Avila CobosCenter for Medical Genetics, Ghent University Hospital, and Cancer Research Institute Ghent (CRIG), Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-8816-9243
Enrique LastraUnit of Genetic Counseling in Cancer, Complejo Hospitalario de Burgos, 09006 Burgos, Spain.
Luis E AbellaUnit of Genetic Counseling in Cancer, Hospital Universitario Rio Hortega, 47012 Valladolid, Spain.
Virginia de la CruzUnit of Genetic Counseling in Cancer, Hospital Universitario Rio Hortega, 47012 Valladolid, Spain.
Carmen D LobatónCancer Genetics Group, Instituto de Biología y Genética Molecular (UVa-CSIC), 47003 Valladolid, Spain.ORCID 0000-0001-9574-3082
Kathleen B ClaesCenter for Medical Genetics, Ghent University Hospital, and Cancer Research Institute Ghent (CRIG), Ghent University, 9000 Ghent, Belgium.
Mercedes DuránCancer Genetics Group, Instituto de Biología y Genética Molecular (UVa-CSIC), 47003 Valladolid, Spain.ORCID 0000-0002-6301-9732
Mar InfanteCancer Genetics Group, Instituto de Biología y Genética Molecular (UVa-CSIC), 47003 Valladolid, Spain.ORCID 0000-0002-7197-5249
Instituto de Biomedicina y Genética Molecular de Valladolid · ESGhent University Hospital · BEHospital Universitario Río Hortega · ESHospital Universitario de Burgos · ES

Funding

Regional Government of Castilla y León ORDEN EDU/1083/2013Universiteit Gent BOF15/GOA/011/Universiteit Gent BOF.DOC.2017.0026.01
6 · The paper itself

Abstract

In this study, we aim to gain insight in the germline mutation spectrum of

Indexed as

clinical guidelinesfamily historygenetic testingHBOCtherapeutic selectionvariant prioritisation

Identifiers

PMID32756499
PMCPMC7465232
OpenAlexW3046635079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.