Evidence map›Paper›PMID 32756496›Full record

ArticleJournal of clinical medicine2020

Clinical and Functional Characteristics of Patients with Unclassifiable Interstitial Lung Disease (uILD): Long-Term Follow-Up Data from European IPF Registry (eurIPFreg).

Ekaterina Krauss, Mustapha El-Guelai, Joern Pons-Kuehnemann, Ruth C Dartsch, Silke Tello, Martina Korfei, Poornima Mahavadi, Andreas Breithecker, Ludger Fink, Mark Stoehr and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Mycophenolate and azathioprine in fibrotic interstitial lung disease.American journal of respiratory and critical care medicine · 2026
    Observational
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  8. Validation of Proposed Criteria for Progressive Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2023
    Article
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  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Ekaterina KraussEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.ORCID 0000-0001-8682-4294
Mustapha El-GuelaiEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.
Joern Pons-KuehnemannMedical Statistics, Institute of Medical Informatics, Justus-Liebig University of Giessen; 35392 Giessen, Germany.
Ruth C DartschEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.
Silke TelloEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.
Martina KorfeiEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.ORCID 0000-0001-8177-2085
Poornima MahavadiEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.ORCID 0000-0002-7580-4738
Andreas BreitheckerUniversities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), 35392 Giessen, Germany.
Ludger FinkUniversities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), 35392 Giessen, Germany.
Mark StoehrEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.
Raphael W MajeedEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.
Werner SeegerEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.
Bruno CrestaniEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.ORCID 0000-0002-2961-3455
Andreas GuentherEuropean IPF Registry & Biobank (eurIPFreg/bank), 35392 Giessen, Germany.
German Center for Lung Research · DEHôpital Bichat-Claude-Bernard · FRJustus-Liebig-Universität Gießen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Aim of the study: In spite of extensive research, up to 20% of interstitial lung diseases (ILD) patients cannot be safely classified. We analyzed clinical features, progression factors, and outcomes of unclassifiable ILD (uILD). (2) Methods: A total of 140 uILD subjects from the University of Giessen and Marburg Lung Center (UGMLC) were recruited between 11/2009 and 01/2019 into the European Registry for idiopathic pulmonary fibrosis (eurIPFreg) and followed until 01/2020. The diagnosis of uILD was applied only when a conclusive diagnosis could not be reached with certainty. (3) Results: In 46.4% of the patients, the uILD diagnosis was due to conflicting clinical, radiological, and pathological data. By applying the diagnostic criteria of usual interstitial pneumonia (UIP) based on computed tomography (CT), published by the Fleischner Society, 22.2% of the patients displayed a typical UIP pattern. We also showed that forced vital capacity (FVC) at baseline (

Indexed as

European Registry for idiopathic pulmonary fibrosis (eurIPFreg)Health-related quality of life (HRQoL)idiopathic pulmonary fibrosis (IPF)interstitial lung diseases (ILD)unclassifiable interstitial lung disease (uILD)

Identifiers

PMID32756496
PMCPMC7464480
OpenAlexW3046994477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.