Evidence map›Paper›PMID 32756423›Full record

ArticleBrain sciences2020

Functional Network Mapping Reveals State-Dependent Response to IGF1 Treatment in Rett Syndrome.

Conor Keogh, Giorgio Pini, Ilaria Gemo, Walter E Kaufmann, Daniela Tropea

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Identification of aFrontiers in molecular neuroscience · 2022
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Conor KeoghDepartment of Surgery, University Hospital Limerick, V94 F858 Limerick, Ireland.
Giorgio PiniTuscany Rett Center, Ospedale Versilia, SS 1 Via Aurelia, 335, 55041 Camaiore LU, Italy.ORCID 0000-0001-6949-2822
Ilaria GemoTuscany Rett Center, Ospedale Versilia, SS 1 Via Aurelia, 335, 55041 Camaiore LU, Italy.
Walter E KaufmannDepartment of Human Genetics, Emory University School of Medicine; Whitehead Biomedical Research Building, 615 Michael Street, Suite 301, Atlanta, GA 30322, USA.
Daniela TropeaNeuropsychiatric Genetics, Trinity Centre for Health Sciences, St. James Hospital, D08 NHY1 Dublin, Ireland.
Ospedale Versilia · ITEmory University · USSt. James's Hospital · IEUniversity Hospital Limerick · IE

Funding

Meath Foundation Ireland Research Award 2019
6 · The paper itself

Abstract

Rett Syndrome (RTT) is a neurodevelopmental disorder associated with mutations in the gene

Indexed as

EEGelectrophysiologyIGF1machine learningnetworkRett Syndrome

Identifiers

PMID32756423
PMCPMC7465931
OpenAlexW3046255814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.