Evidence map›Paper›PMID 32756369›Full record

ReviewNanomaterials (Basel, Switzerland)2020

Melanin and Melanin-Like Hybrid Materials in Regenerative Medicine.

Chiara Cavallini, Giuseppe Vitiello, Barbara Adinolfi, Brigida Silvestri, Paolo Armanetti, Paola Manini, Alessandro Pezzella, Marco d'Ischia, Giuseppina Luciani, Luca Menichetti

Open access · goldAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Review
  3. The Impact of Sleep Quality on Skin Color.Indian dermatology online journal · 2025
    Article
  4. Article
  5. International journal of molecular sciences · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Functionalization of and through Melanin: Strategies and Bio-Applications.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chiara CavalliniInstitute of Clinical Physiology, National Research Council, via Giuseppe Moruzzi 1, 56124 Pisa, Italy.
Giuseppe VitielloDepartment of Chemical, Materials and Production Engineering (DICMaPI), University of Naples Federico II, Piazzale V. Tecchio 80, 80125 Napoli, Italy.ORCID 0000-0003-3389-6942
Barbara AdinolfiInstitute of Applied Physics "Nello Carrara", National Research Council, via Madonna del Piano 10, 50019 Sesto Fiorentino, FI, Italy.
Brigida SilvestriDepartment of Chemical, Materials and Production Engineering (DICMaPI), University of Naples Federico II, Piazzale V. Tecchio 80, 80125 Napoli, Italy.ORCID 0000-0003-1654-8698
Paolo ArmanettiInstitute of Clinical Physiology, National Research Council, via Giuseppe Moruzzi 1, 56124 Pisa, Italy.
Paola ManiniDepartment of Chemical Sciences, University of Naples Federico II, via Cintia 21, I-80126 Napoli, Italy.
Alessandro PezzellaDepartment of Chemical Sciences, University of Naples Federico II, via Cintia 21, I-80126 Napoli, Italy.
Marco d'IschiaDepartment of Chemical Sciences, University of Naples Federico II, via Cintia 21, I-80126 Napoli, Italy.
Giuseppina LucianiDepartment of Chemical, Materials and Production Engineering (DICMaPI), University of Naples Federico II, Piazzale V. Tecchio 80, 80125 Napoli, Italy.
Luca MenichettiInstitute of Clinical Physiology, National Research Council, via Giuseppe Moruzzi 1, 56124 Pisa, Italy.ORCID 0000-0002-3293-9616
University of Naples Federico II · ITIstituto di Fisiologia Clinica · ITNello Carrara Institute of Applied Physics · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanins are a group of dark insoluble pigments found widespread in nature. In mammals, the brown-black eumelanins and the reddish-yellow pheomelanins are the main determinants of skin, hair, and eye pigmentation and play a significant role in photoprotection as well as in many biological functions ensuring homeostasis. Due to their broad-spectrum light absorption, radical scavenging, electric conductivity, and paramagnetic behavior, eumelanins are widely studied in the biomedical field. The continuing advancements in the development of biomimetic design strategies offer novel opportunities toward specifically engineered multifunctional biomaterials for regenerative medicine. Melanin and melanin-like coatings have been shown to increase cell attachment and proliferation on different substrates and to promote and ameliorate skin, bone, and nerve defect healing in several in vivo models. Herein, the state of the art and future perspectives of melanins as promising bioinspired platforms for natural regeneration processes are highlighted and discussed.

Indexed as

bone tissue engineeringeumelaninmelaninmelanin hybridsmelanin-like materialsneural tissue engineeringpolydopamineregenerative medicinewound healing

Identifiers

PMID32756369
PMCPMC7466405
OpenAlexW3046359816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.