Evidence map›Paper›PMID 32756350›Full record

ArticleBiomedicines2020

The Effectiveness of Multi-Session FMT Treatment in Active Ulcerative Colitis Patients: A Pilot Study.

Dorota Mańkowska-Wierzbicka, Marta Stelmach-Mardas, Marcin Gabryel, Hanna Tomczak, Marzena Skrzypczak-Zielińska, Oliwia Zakerska-Banaszak, Anna Sowińska, Dagmara Mahadea, Alina Baturo, Łukasz Wolko and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Gut microbiota and atrial cardiomyopathy.Frontiers in cardiovascular medicine · 2025
    Review
  11. Gut bacteria: an etiological agent in human pathological conditions.Frontiers in cellular and infection microbiology · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Sex, puberty, and the gut microbiome.Reproduction (Cambridge, England) · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Dorota Mańkowska-WierzbickaDepartment of Gastroenterology, Dietetics and Internal Medicine, Poznan University of Medical Sciences, Heliodor Święcicki Hospital, Przybyszewskiego 49, 60-355 Poznań, Poland.ORCID 0000-0003-2577-5905
Marta Stelmach-MardasDepartment of Biophysics, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland.ORCID 0000-0001-5944-1642
Marcin GabryelDepartment of Gastroenterology, Dietetics and Internal Medicine, Poznan University of Medical Sciences, Heliodor Święcicki Hospital, Przybyszewskiego 49, 60-355 Poznań, Poland.
Hanna TomczakDepartment of Dermatology and Venereology, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznań, Poland.
Marzena Skrzypczak-ZielińskaInstitute of Human Genetics, Polish Academy of Sciences, Strzeszyńska 32, 60-479 Poznań, Poland.ORCID 0000-0001-5313-107X
Oliwia Zakerska-BanaszakInstitute of Human Genetics, Polish Academy of Sciences, Strzeszyńska 32, 60-479 Poznań, Poland.
Anna SowińskaDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, Rokietnicka 7, 60-806 Poznań, Poland.
Dagmara MahadeaDepartment of Gastroenterology, Dietetics and Internal Medicine, Poznan University of Medical Sciences, Heliodor Święcicki Hospital, Przybyszewskiego 49, 60-355 Poznań, Poland.
Alina BaturoDepartment of Gastroenterology, Dietetics and Internal Medicine, Poznan University of Medical Sciences, Heliodor Święcicki Hospital, Przybyszewskiego 49, 60-355 Poznań, Poland.
Łukasz WolkoDepartment of Biochemistry and Biotechnology, University of Life Sciences, Dojazd 11, 60-632 Poznań, Poland.ORCID 0000-0002-3626-4388
Ryszard SłomskiInstitute of Human Genetics, Polish Academy of Sciences, Strzeszyńska 32, 60-479 Poznań, Poland.ORCID 0000-0001-5601-7002
Agnieszka DobrowolskaDepartment of Gastroenterology, Dietetics and Internal Medicine, Poznan University of Medical Sciences, Heliodor Święcicki Hospital, Przybyszewskiego 49, 60-355 Poznań, Poland.
Poznan University of Medical Sciences · PLInstitute of Human Genetics · PLUniversity of Life Sciences in Poznań · PL

Funding

grant for young scientists from Poznan University of Medical Sciences, Poznan, Poland 502-01-222-38-000
6 · The paper itself

Abstract

The modification of the microbiome through fecal microbiota transplantation (FMT) is becoming a very promising therapeutic option for inflammatory bowel disease (IBD) patients. Our pilot study aimed to assess the effectiveness of multi-session FMT treatment in active ulcerative colitis (UC) patients. Ten patients with UC were treated with multi-session FMT (200 mL) from healthy donors, via colonoscopy/gastroscopy. Patients were evaluated as follows: at baseline, at week 7, and after 6 months, routine blood tests (including C reactive protein (CRP) and calprotectin) were performed. 16S rRNA gene (V3V4) sequencing was used for metagenomic analysis. The severity of UC was classified based on the Truelove-Witts index. The assessment of microbial diversity showed significant differences between recipients and healthy donors. FMT contributed to long-term, significant clinical and biochemical improvement. Metagenomic analysis revealed an increase in the amount of

Indexed as

fecal microbiota transplantation (FMT)gut microbiotainflammatory bowel disease (IBD)ulcerative colitis (UC)

Identifiers

PMID32756350
PMCPMC7459721
OpenAlexW3046785006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.