ArticleMaterials (Basel, Switzerland)2020
Crosslinking of Chitosan with Dialdehyde Chitosan as a New Approach for Biomedical Applications.
Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The trial behind it
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Who cites it
29 citing papers in PubMed, 135 citations in OpenAlex.
- Green Deep Eutectic Solvents for Functionalizing Chitosan-Dialdehyde Materials with Varied Crosslinker Content.Materials (Basel, Switzerland) · 2026Article
- Application of chitosan-based nanogels for dermal and transdermal delivery systems.Journal of materials science. Materials in medicine · 2025Review
- Review
- Three-Dimensional Printing and Supercritical Technologies for the Fabrication of Intricately Structured Aerogels Derived from the Alginate-Chitosan Polyelectrolyte Complex.Gels (Basel, Switzerland) · 2025Article
- Design and Evaluation of a Crosslinked Chitosan-Based Scaffold Containing Hyaluronic Acid for Articular Cartilage Reconstruction.Molecules (Basel, Switzerland) · 2025Article
- Ionotropic Gelation and Chemical Crosslinking as Tools to Obtain Gellan Gum-Based Beads with Mesalazine.Pharmaceutics · 2025Article
- Enhancing Performance of Silicone Hydrogel Contact Lenses with Hydrophilic Polyphenolic Coatings.Journal of functional biomaterials · 2024Article
- Cross-Linking Agents in Three-Component Materials Dedicated to Biomedical Applications: A Review.Polymers · 2024Review
- The Impact of the Methacrylation Process on the Usefulness of Chitosan as a Biomaterial Component for 3D Printing.Journal of functional biomaterials · 2024Article
- Enhancing the porosity of chitosan sponges with CBD by adding antimicrobial violacein.Heliyon · 2024Article
- Poly (Vinyl Alcohol) Hydrogels Boosted with Cross-Linked Chitosan and Silver Nanoparticles for Efficient Adsorption of Congo Red and Crystal Violet Dyes.Gels (Basel, Switzerland) · 2023Article
- Bisphosphonate-incorporated coatings for orthopedic implants functionalization.Materials today. Bio · 2023Review
- Chitosan Based Materials in Cosmetic Applications: A Review.Molecules (Basel, Switzerland) · 2023Review
- PVA/Chitosan Thin Films Containing Silver Nanoparticles and Ibuprofen for the Treatment of Periodontal Disease.Polymers · 2022Article
- Chitosan-based films with cannabis oil as a base material for wound dressing application.Scientific reports · 2022Article
- Detailed Structural Characterization of Oxidized Sucrose and Its Application in the Fully Carbohydrate-Based Preparation of a Hydrogel from Carboxymethyl Chitosan.Molecules (Basel, Switzerland) · 2022Article
- Chitosan-Gelatin Films Cross-Linked with Dialdehyde Cellulose Nanocrystals as Potential Materials for Wound Dressings.International journal of molecular sciences · 2022Article
- Dialdehyde Starch Nanocrystals as a Novel Cross-Linker for Biomaterials Able to Interact with Human Serum Proteins.International journal of molecular sciences · 2022Article
- Scaffolds Loaded with Dialdehyde Chitosan and Collagen-Their Physico-Chemical Properties and Biological Assessment.Polymers · 2022Article
- The Use of Chitosan and Starch-Based Flocculants for Filter Backwash Water Treatment.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Materials based on natural high molecular compounds are particularly interesting for biomedical applications. It is known that the cross-linking agent used for preparation of biomacromolecule-based materials is as important as used biopolymer. Therefore, natural cross-linkers containing reactive carbonyl groups are of great interest especially for modifying properties of natural polysaccharides. One of the most popular cross-linking agents is glutaraldehyde. Nevertheless, the unreacted particles can be released from the cross-linked material and cause cytotoxic effects. This can be eliminated when using a cross-linker based e.g., on polysaccharides. This article describes quick and efficient synthesis of dialdehyde chitosan (DACS) and its application for the preparation of chitosan films. Materials obtained with different amount of DACS were fully characterized in terms of structure and surface morphology. Thermal and mechanical properties as well as hydrophilic character were also examined. The results obtained were compared with the materials obtained by cross-linking chitosan with low molecular weight glutaraldehyde and high molecular weight cross-linking agent based on polysaccharide-dialdehyde starch. Toxicity of all obtained materials was tested using the Microtox
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.