ArticleJournal of clinical medicine2020
Living-Donor Uterus Transplantation: Pre-, Intra-, and Postoperative Parameters Relevant to Surgical Success, Pregnancy, and Obstetrics with Live Births.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Maternal and perinatal outcomes of live births after uterus transplantation: A systematic review.Acta obstetricia et gynecologica Scandinavica · 2025Pooled it
- Anesthesia for uterine transplantation.Anesthesia and pain medicine · 2026Review
- Risks of uterus transplantation: a scoping review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Article
- Uterus transplantation: A bibliometric review of six-decade study from 1960 to 2024.Acta obstetricia et gynecologica Scandinavica · 2025Review
- The costs per live birth after uterus transplantation: results of the Swedish live donor trial.Human reproduction (Oxford, England) · 2025Article
- Past, Present, and Future: A Review of Uterus Transplant.Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- Living-Donor Uterus Transplantation: A Clinical Review.Journal of clinical medicine · 2024Review
- Reproducibility of Rejection Grading in Uterus Transplantation: A Multicenter Study.Transplantation direct · 2023Article
- Uterus transplantation: from research, through human trials and into the future.Human reproduction update · 2023Review
- Graft Failure after Uterus Transplantation in 16 Recipients: A Review.Journal of clinical medicine · 2023Review
- Differences between living and deceased donation in human uterus transplantation: A narrative review.International journal of reproductive biomedicine · 2023Review
- Uterine allograft removal by total laparoscopic hysterectomy after successful cesarean delivery in a living-donor uterus recipient with uterovaginal agenesis (MRKHS).Archives of gynecology and obstetrics · 2023Article
- Early Uterine Transplant Graft Loss Due to Thrombosis: Single-Center Experience With Causes, Prevention, Diagnosis, and Treatment.Physiological research · 2022Article
- Uterus Transplantation: From a Deceased Donor or Living Donor?Journal of clinical medicine · 2022Article
- Radiologic Evaluation of Uterine Vasculature of Uterus Transplant Living Donor Candidates: DUETS Classification.Journal of clinical medicine · 2022Article
- Histopathological examination of the ectocervical biopsy in non-transplanted uteri: A study contributing to the provisional scoring system of subclinical graft rejection after uterus transplantation.Acta obstetricia et gynecologica Scandinavica · 2022Observational
- Uterus transplantation: state of the art in 2021.Journal of assisted reproduction and genetics · 2021Review
- Towards a bioengineered uterus: bioactive sheep uterus scaffolds are effectively recellularized by enzymatic preconditioning.NPJ Regenerative medicine · 2021Article
- Human Uterus Transplantation from Living and Deceased Donors: The Interim Results of the First 10 Cases of the Czech Trial.Journal of clinical medicine · 2021Article
- Review
Corrections and comments
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Authors and funding
34 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uterus transplantation (UTx) can provide a route to motherhood for women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS), a congenital disorder characterized by uterovaginal aplasia, but with functional ovaries. Based on our four successful living-donor transplantations and two resulting births, this analysis presents parameters relevant to standardizing recipient/donor selection, UTx surgery, and postoperative treatment, and their implementation in routine settings. We descriptively analyzed prospectively collected observational data from our four uterus recipients, all with MRKHS, their living donors, and the two newborns born to two recipients, including 1-year postnatal follow-ups. Analysis included only living-donor/recipient pairs with completed donor/recipient surgery. Two recipients, both requiring ovarian restimulation under immunosuppression after missed pregnancy loss in one case and no pregnancy in the other, each delivered a healthy boy by cesarean section. We conclude that parameters crucial to successful transplantation, pregnancy, and childbirth include careful selection of donor/recipient pairs, donor organ quality, meticulous surgical technique, a multidisciplinary team approach, and comprehensive follow-up. Surgery duration and blood vessel selection await further optimization, as do the choice and duration of immunosuppression, which are crucial to timing the first embryo transfer. Data need to be collected in an international registry due to the low prevalence of MRKHS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.