Evidence map›Paper›PMID 32756215›Full record

ArticleMedicine2020

Therapeutic response to corticosteroids in a critically ill patient with COVID-19: A case report.

Kaige Wang, Fen Tan, Rui Zhou, Dan Liu, Zhong Ni, Jiasheng Liu, Fengming Luo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Corticosteroids for COVID-19: worth it or not?Molecular biology reports · 2022
    Review
  5. Occurrence, Fate, Effects, and Risks of Dexamethasone: Ecological Implications Post-COVID-19.International journal of environmental research and public health · 2021
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Kaige WangDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu.
Fen TanDepartment of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Respiratory Disease Research Institute of Hunan Province, Changsha.ORCID 0000-0001-9083-4161
Rui ZhouDepartment of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Respiratory Disease Research Institute of Hunan Province, Changsha.
Dan LiuDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu.
Zhong NiDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu.
Jiasheng LiuDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Fengming LuoDepartment of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu.
West China Hospital of Sichuan University · CNCentral South University · CNRenmin Hospital of Wuhan University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSince the coronavirus disease 2019 (COVID-19) outbreak in Wuhan in late 2019, controversy on the use of corticosteroids for COVID-19 has obtained increasing attention. We present 1 critically ill patient who had a rapid therapeutic response to moderate-dose corticosteroids. PATIENT CONCERNS: A 53-year-old critically ill woman from Wuhan suffered with COVID-19. DIAGNOSIS: The chest computed tomography scan was suggestive of COVID-19. The diagnosis was confirmed by a real-time reverse transcription polymerase chain reaction test for SARS-CoV-2. The critically ill status was characterized by worsening dyspnea, progressing bilateral lung consolidation, and poor oxygenation (SiO2/FiO2:110 mm Hg).

interventionsThe patient was treated with a moderate dose of intravenous corticosteroids and high-flow nasal cannula oxygen therapy. OUTCOMES: After the initiation of corticosteroids, the patient rapidly improved over the following 6 days. Serial chest computed tomography scans showed good absorption of the consolidations. The patient was discharged on Day 17 of hospitalization without obvious adverse effects.

conclusionsEarly use of moderate-dose corticosteroids over a short period may enhance recovery from COVID-19 in critically ill patients.

Indexed as

Adrenal Cortex HormonesBetacoronavirusCombined Modality TherapyCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentFemaleHumansMiddle AgedOxygen Inhalation TherapyPandemicsPneumonia, ViralSARS-CoV-2Treatment OutcomeAdrenal Cortex Hormones

Identifiers

PMID32756215
PMCPMC7402741
OpenAlexW3046488929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.