ArticleMedicine2020
Measurements of scleral thickness and corneal optic densitometry in patients with systemic lupus erythematosus.
Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Analysis of central corneal thickness in systemic lupus erythematosus.Frontiers in medicine · 2025Article
- Swept-source optical coherence tomography in ocular surface diseases: anterior segment analysis repeatability and its limits.Frontiers in medicine · 2024Article
- Association between central corneal thickness and systemic lupus erythematosus: a cross-sectional study protocol.Frontiers in medicine · 2024Article
- Scleral changes in systemic lupus erythematosus patients using swept source optical coherence tomography.Frontiers in immunology · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to evaluate the scleral thickness and corneal parameters of patients with systemic lupus erythematosus (SLE).
methodsForty-seven eyes of 47 SLE patients and 44 eyes of healthy controls were included in this cross-sectional study. Anterior segment optical coherence tomography (AS-OCT) was used to measure the corneal and scleral thickness. Scleral thickness (ST) was measured based upon the segmentation at 1000 to 5000 μm from the scleral spur. Pentacam HR was used to measure corneal parameters.
resultsThere was no statistically significant difference between SLE group and control group according to age and sex (P > .05). The ST measurements at all distances from scleral spur were found to be thicker in patients with SLE (P < .05). Central corneal thickness (CCT), cornea volume (CV), corneal densitometry (CD), and peripheral corneal thickness (PCT) measurements were similar between the groups (P > .05).
conclusionST was thicker in SLE patients compared with healthy controls. AS-OCT seems helpful in selecting optimal sites for pharmaceutical or surgical intervention in SLE patients, since it shows thickness variations in anterior sclera.
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Registered trials
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