Evidence map›Paper›PMID 32755566›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2020

Role of METTL3-Dependent N

Mu-Di Yao, Qin Jiang, Yan Ma, Chang Liu, Chuan-Yan Zhu, Ya-Nan Sun, Kun Shan, Hui-Min Ge, Qiu-Yang Zhang, Hui-Ying Zhang and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it, 127 citations in OpenAlex.

  1. RNA methylation in vascular disease: a systematic review.Journal of cardiothoracic surgery · 2022
    Pooled it
  2. Pooled it
  3. Article
  4. METTL14-dependent NExperimental & molecular medicine · 2026
    Article
  5. Article
  6. METTL3 mediates mJournal of advanced research · 2026
    Article
  7. The Prognostic and Predictive Value of METTL3 in Metastatic Colorectal Cancer.Asian Pacific journal of cancer prevention : APJCP · 2026
    Article
  8. mInternational journal of molecular medicine · 2026
    Review
  9. Article
  10. Article
  11. MFrontiers in genetics · 2026
    Review
  12. Article
  13. Beyond transcription: RNA-binding proteins steering angiogenesis.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Subgenome Dominance in Allotetraploid Actinidia valvata Regulates RNA mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  18. Article
  19. [Eye acupuncture improves neural function in rats with cerebral ischemia-reperfusion injury by promoting angiogenesisNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Mu-Di YaoEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Qin JiangThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Yan MaThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Chang LiuEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Chuan-Yan ZhuThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Ya-Nan SunEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Kun ShanEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Hui-Min GeThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Qiu-Yang ZhangThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Hui-Ying ZhangThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Jin YaoThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Xiu-Miao LiThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China; The Fourth School of Clinical Medicine, Nanjing Medical University, Nanjing, China.
Biao YanEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai 200031, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China. Electronic address: biao.yan@fdeent.org.
Second Affiliated Hospital of Nanjing Medical University · CNEye & ENT Hospital of Fudan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic alterations occur in many physiological and pathological processes. N

Indexed as

Epigenesis, GeneticGene Expression RegulationAdenosineAnimalsBiomarkersDisease SusceptibilityGene SilencingHumansHypoxiaMethyltransferasesMiceMice, KnockoutNeovascularization, PathologicRetinal DiseasesRNA, MessengerWnt Signaling PathwayAdenosineBiomarkersMethyltransferasesMettl3 protein, mouseN-methyladenosineRNA, Messengerangiogenesism(6)A modificationMETTL3oxygen-induced retinopathyWnt signaling

Identifiers

PMID32755566
PMCPMC7545007
OpenAlexW3045166465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.