Evidence map›Paper›PMID 32755440›Full record

ArticleHuman vaccines & immunotherapeutics2021

Pertussis in early life: underdiagnosed, severe, and risky disease. A seven-year experience in a pediatric tertiary-care hospital.

Chiara Di Camillo, Anna Chiara Vittucci, Livia Antilici, Claudia Ciarlitto, Giulia Linardos, Carlo Concato, Laura Lancella, Alberto Villani

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  8. Frontiers in microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chiara Di CamilloAcademic Department of Pediatrics, Pediatric and Infectious Disease Unit, Children's Hospital Bambino Gesù (IRCCS), Rome, Italy.
Anna Chiara VittucciAcademic Department of Pediatrics, Pediatric and Infectious Disease Unit, Children's Hospital Bambino Gesù (IRCCS), Rome, Italy.ORCID 0000-0002-1164-5563
Livia AntiliciAcademic Department of Pediatrics, Tor Vergata University of Rome, Rome, Italy.ORCID 0000-0001-5653-6638
Claudia CiarlittoAcademic Department of Pediatrics, Tor Vergata University of Rome, Rome, Italy.ORCID 0000-0001-9946-665X
Giulia LinardosVirology Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy.ORCID 0000-0003-4782-8158
Carlo ConcatoVirology Unit, Bambino Gesù Children's Hospital (IRCCS), Rome, Italy.
Laura LancellaAcademic Department of Pediatrics, Pediatric and Infectious Disease Unit, Children's Hospital Bambino Gesù (IRCCS), Rome, Italy.
Alberto VillaniAcademic Department of Pediatrics, Pediatric and Infectious Disease Unit, Children's Hospital Bambino Gesù (IRCCS), Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimPertussis continues to be a common worldwide infection in pediatric and adult populations.We aimed to study epidemiological and clinical characteristics of infants and children admitted for pertussis to a tertiary-care hospital and to investigate the risk factors for pediatric intensive care unit (PICU) admission. MATERIALS AND

methodsWith a retrospective study, we analyzed all medical reports of patients admitted to Bambino Gesù Children's Hospital in Rome from January 2011 to December 2018 with a diagnosis of pertussis.

resultsWe examined 195 patients. The majority of hospitalized children (66.15%) were <3 months of age. No mother had received pertussis containing vaccine during pregnancy. Ten cases required admission in PICU. The age at admission was lower in PICU patients with respect to ward patients (42.8 vs 240 days;

conclusionsPertussis is a remerging disease. In infants, it is associated with significant morbidity and mortality. In recent years, many countries have implemented different vaccination strategies and public health measures to prevent the increase in pertussis cases. Maternal vaccination has been shown to be highly protective for infants <3 months of age before they can develop their own immunity via vaccination.

Indexed as

Whooping CoughChildHumansInfantIntensive Care Units, PediatricPertussis VaccineRetrospective StudiesTertiary Care CentersPertussis VaccineBordetella pertussisinfantsleukocytosispregnancyvaccine

Identifiers

PMID32755440
PMCPMC7993225

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.