ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2020
Relationship between distension-contraction waveforms during esophageal peristalsis: effect of bolus volume, viscosity, and posture.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Rhythmic contraction but arrhythmic distension of esophageal peristaltic reflex in patients with dysphagia.PloS one · 2022Trial
- Esophageal peristalsis in health and disease: mechanistic insights.Physiological reviews · 2026Review
- Beyond the Surface: Exploring Altered Esophageal Distensibility and Compliance in Eosinophilic Esophagitis.Digestive diseases and sciences · 2026Review
- Phrenic Ampulla Emptying Dysfunction in Patients with Esophageal Symptoms.Journal of neurogastroenterology and motility · 2024Article
- Why so Many Patients With Dysphagia Have Normal Esophageal Function Testing.Gastro hep advances · 2024Article
- Esophageal wall compliance/stiffness during peristalsis in patients with functional dysphagia and high-amplitude esophageal contractions.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- Distension contraction plots of pharyngeal/esophageal peristalsis: next frontier in the assessment of esophageal motor function.American journal of physiology. Gastrointestinal and liver physiology · 2022Review
- Bolus flow and biomechanical properties of the esophageal wall during primary esophageal peristalsis: Effects of bolus viscosity and posture.Neurogastroenterology and motility · 2022Article
- Esophageal Bolus Domain Pressure and Peristalsis Associated With Experimental Induction of Esophagogastric Junction Outflow Obstruction.Journal of neurogastroenterology and motility · 2022Article
- Distension-contraction profile of peristalsis in patients with nutcracker esophagus.Neurogastroenterology and motility · 2021Article
- Novel gel bolus to improve impedance-based measurements of esophageal cross-sectional area during primary peristalsis.Neurogastroenterology and motility · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
High-resolution esophageal manometry (HRM) in its current form assesses only the contraction phase of peristalsis. Degree of esophageal distension ahead of contraction is a surrogate of relaxation and can be measured from intraluminal esophageal impedance measurements. The characteristics of esophageal contractions, i.e., their amplitude, duration, velocity, and modulating factors, have been well studied. We studied the effect of bolus volume and viscosity and posture on swallow-induced distension and contraction and the temporal relationship between the two. HRM impedance recordings of 50 healthy subjects with no esophageal symptoms were analyzed. Eight to ten swallows of 5 and 10 mL of 0.5 N saline and a viscous bolus were recorded in the supine and Trendelenburg positions. Custom-built computer software generated the distension-contraction plots and numerical data of the amplitudes of distension (cross-sectional area) and contraction, and the temporal relationship between distension and peak contraction. The hallmarks of distension waveforms are that
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