Evidence map›Paper›PMID 32755028›Full record

ArticleBrain and behavior2020

Reduced thiamine is a predictor for cognitive impairment of cerebral infarction.

Liang Feng, Weilei He, Guiqian Huang, Shasha Lin, Chengxiang Yuan, Haoran Cheng, Jincai He, Yiming Liu

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Liang FengDepartment of Neurology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0002-9686-0464
Weilei HeDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Guiqian HuangDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Shasha LinDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Chengxiang YuanDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Haoran ChengDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Jincai HeDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.ORCID 0000-0002-5493-4357
Yiming LiuDepartment of Neurology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0001-7200-7197
Wenzhou Medical University · CNQilu Hospital of Shandong University · CN

Funding

Projects of National Natural Science Foundation of China 81873799
6 · The paper itself

Abstract

objectiveReduced thiamine (vitamin B MATERIALS AND

methodsOne hundred and eighty two patients with acute cerebral infarction were recruited within the first 24 hr after admission. Thiamine and other vitamin Bs of peripheral blood samples were measured. Patients were divided into with poststroke cognitive impairment (PSCI) and non-PSCI according to the score of MMSE and the degree of education.

resultsReduced thiamine (<1.0 ng/ml) was independently associated with PSCI (OR: 2.033, 95% CI: 1.017-4.067, p = .045) after adjusting for potential confounding factors. Advanced age, lower education, diabetes mellitus, left hemisphere infarction, and higher National Institute of Health Stroke Scale (NIHSS) were also independent risk factors for PSCI.

conclusionsReduced thiamine is one of the predictors for early cognitive impairment in patients with acute cerebral infarction.

Indexed as

Brain IschemiaCognitive DysfunctionStrokeCerebral InfarctionHumansThiamineThiaminecerebral infarctioncognitive impairmentdementiastrokethiamine

Identifiers

PMID32755028
PMCPMC7507112
OpenAlexW3047291650

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.