ArticleEnvironmental science and pollution research international2020
Study of occupational exposure to brick kiln emissions on heavy metal burden, biochemical profile, cortisol level and reproductive health risks among female workers at Rawat, Pakistan.
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Pollution, stress response, and obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- Optimizing Fuel-Based Environmental Strategies for Stack Emissions From Zigzag and Fixed Chimney Bull's Trench Kiln (FCBTK) Brick Kilns: A Comparative Analysis.International journal of analytical chemistry · 2026Article
- Exploring the Molecular Mechanism of Hepatic Dysfunction Among Workers Exposed to Nickel and Chromium in Electroplating.International journal of molecular sciences · 2025Article
- Detection of reproductive and hematobiochemical biomarkers to evaluate the impact of heavy metal exposure on brick kiln workers.Scientific reports · 2025Article
- Article
- Mediation Effect of Body Mass Index on the Association of Urinary Nickel Exposure with Serum Lipid Profiles.Biological trace element research · 2023Article
- A Molecular Mechanism to Explain the Nickel-Induced Changes in Protamine-like Proteins and Their DNA Binding Affecting Sperm Chromatin inBiomolecules · 2023Article
- Biochemical and reproductive biomarker analysis to study the consequences of heavy metal burden on health profile of male brick kiln workers.Scientific reports · 2022Article
- Zig-zag technology adoption behavior among brick kiln owners in Pakistan.Environmental science and pollution research international · 2021Article
- Does gender equality in education matter for environmental sustainability in sub-Saharan Africa?Environmental science and pollution research international · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was planned to understand the heavy metal burden and its possible actions in blood of occupational females working at brick kilns at Rawat, Pakistan. A total of 232 women were included in the study, of which 114 presented control subjects. Apart from collection of demographic data, fertility indicators and body mass index (BMI), blood was collected from subjects that was later used for the determination of heavy metal concentrations using atomic absorption spectroscopy and haematological profile. Blood was centrifuged and plasma was obtained and stored at - 20° to study biochemical variables (sodium dismutase, peroxidase, reactive oxygen species, thiobarbituric acid reactive species, protein estimation), lipid profile and cortisol concentrations among the two groups. Analysis of heavy metal in blood showed elevated levels of cadmium (3.09 ± 0.01 μg/dl), chromium (4.20 ± 0.02 μg/dl) and nickel (5.59 ± 0.03 μg/dl) in worker's group as compared with control. Increased platelet count; decreased antioxidant enzyme and increased oxidants level; increased total cholesterol, low-density lipoprotein (LDL) and triglyceride (TG); decreased total protein and high-density lipoprotein (HDL); and increased cortisol levels were evident among workers as compared with the control group. The study concluded that occupational workers experience increased heavy metals burden in blood and, therefore, pose a risk to human health by causing reduction in antioxidant enzymes concentration and increase in stress conditions.
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