Evidence map›Paper›PMID 32754848›Full record

Observational studyLangenbeck's archives of surgery2020

Laparoscopic versus open distal gastrectomy for locally advanced gastric cancer in middle-low-volume centers in Western countries: a propensity score matching analysis.

Giovanni Maria Garbarino, Gianluca Costa, Giovanni Guglielmo Laracca, Giorgio Castagnola, Paolo Mercantini, Massimiliano Di Paola, Simone Vita, Luigi Masoni

Open access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Langenbeck's archives of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Giovanni Maria GarbarinoDepartment of Medical Surgical Science and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035-39, 00189, Rome, Italy. giovannimaria.garbarino@uniroma1.it.ORCID http://orcid.org/0000-0003-3373-0328
Gianluca CostaDepartment of Medical Surgical Science and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035-39, 00189, Rome, Italy.
Giovanni Guglielmo LaraccaDepartment of Medical Surgical Science and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035-39, 00189, Rome, Italy.
Giorgio CastagnolaDepartment of Medical Surgical Science and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035-39, 00189, Rome, Italy.
Paolo MercantiniDepartment of Medical Surgical Science and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035-39, 00189, Rome, Italy.
Massimiliano Di PaolaGenaral Surgery Department, San Pietro Fatebenefratelli Hospital, Via Cassia 600, 00189, Rome, Italy.
Simone VitaGenaral Surgery Department, San Pietro Fatebenefratelli Hospital, Via Cassia 600, 00189, Rome, Italy.
Luigi MasoniDepartment of Medical Surgical Science and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035-39, 00189, Rome, Italy.
Fatebenefratelli Hospital · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrectomy with D2 lymphadenectomy is the standard treatment for patients with resectable gastric cancer. Laparoscopic distal gastrectomy (LDG) is routinely performed for early gastric cancer, and its indications are increasing even for locally advanced gastric cancer. The aim of this study is to compare two middle-low-volume centers in Western countries experience on LDG versus open distal gastrectomy (ODG) for locally advanced gastric cancer in terms of surgical and oncological outcomes.

methodsWe reviewed the data of 123 consecutive patients that underwent LDG and ODG with D2 lymphadenectomy between 2009 and 2014. Among them, 91 were eligible for inclusion (46 LDG and 45 ODG). After propensity score matching analysis, using a 1:1 case-control match, 34 patients were stratified for each group.

resultsThe mean operative time was significantly longer in the LDG group (257.2 vs. 197.2, p < 0.001). No differences were observed in terms of intraoperative blood loss, average number of lymph nodes removed, and lymph node metastases. The postoperative morbidity was comparable in the two groups. LDG group had a significant faster bowel canalization and soft oral intake (p < 0.001). The 5-year overall and disease-free survival were higher for patients treated by laparoscopy, but the post-hoc subgroups analysis revealed that the advantage of LDG was significant just in N0 and stage IB-II patients, whereas N+ and stage III patient's survival curves were perfectly superimposable.

conclusionsLDG for locally advanced gastric cancer seems to be feasible and safe with surgical and long-term oncological outcomes comparable with open surgery, even in medium-low-volume centers.

Indexed as

AgedFemaleGastrectomyHumansLaparoscopyLymphatic MetastasisLymph Node ExcisionMaleNeoplasm StagingOperative TimePropensity ScoreRetrospective StudiesStomach NeoplasmsSurvival RateGastric CancerLaparoscopic surgeryLong-term oncological outcomesMiddle–low-volume centersPostoperative recovery

Identifiers

PMID32754848
PMCPMC7471172
OpenAlexW3047614412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.