Evidence map›Paper›PMID 32754722›Full record

ArticleCell reports. Medicine2020

Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during

Daniel T Dugger, Monica Fung, Lorna Zlock, Saharai Caldera, Louis Sharp, Steven R Hays, Jonathan P Singer, Lorriana E Leard, Jefferey A Golden, Rupal J Shah and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Frailty in lung transplant recipients is associated with anemia and telomere dysfunction but independent of epigenetic age.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  2. Article
  3. Airway epithelium in lung transplantation: a potential actor for post-transplant complications?European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Infectious disease reports · 2022
    Article
  8. Review
  9. Can we decloak how infections drive complications after lung transplantation?The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021
    Article
  10. Rapid molecular detection of airway pathogens in lung transplant recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2021
    Observational
  11. Chronic lung allograft dysfunction small airways reveal a lymphocytic inflammation gene signature.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Daniel T DuggerDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Monica FungDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Lorna ZlockDepartment of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
Saharai CalderaDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Louis SharpDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Steven R HaysDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Jonathan P SingerDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Lorriana E LeardDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Jefferey A GoldenDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Rupal J ShahDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Jasleen KukrejaDepartment of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.
Erin GordonDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Walter FinkbeinerDepartment of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
Mary Ellen KleinhenzDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
Chaz LangelierDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
John R GreenlandDepartment of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
University of California, San Francisco · USChan Zuckerberg Initiative (United States) · USSan Francisco VA Medical Center · US

Funding

SynthesisP30DK072517 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VERKMAN, ALAN S · 2005 to 2022
$18.1M
Understanding the Molecular Genetic Mechanisms of Asthma Risk Loci: IL33, IL1RL1, and GSDMB - COVID 19 SupplementR01AI136962 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORDON, ERIN D. · 2018 to 2022
$3.4M
Telomere Dysfunction as a cause of Chronic Lung Allograft DysfunctionR01HL151552 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GREENLAND, JOHN · 2020 to 2024
$1.6M
Profiling the Lung Transcriptome for Precision Diagnosis of Respiratory Infections using Host/Pathogen Metagenomic SequencingK23HL138461 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LANGELIER, CHARLES · 2018 to 2021
$718k
Cytomegalovirus Immune Responses in Chronic Lung Allograft Dysfunction PathogenesisI01CX002011 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI GREENLAND, JOHN · 2020 to 2025
–
Immune Mechanisms of Large-airway Lymphocytic BronchitisIK2CX001034 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI GREENLAND, JOHN · 2015 to 2019
–
CSRD VA I01 CX002011CSRD VA IK2 CX001034NHLBI NIH HHS K23 HL138461NHLBI NIH HHS R01 HL151552NIAID NIH HHS R01 AI136962NIDDK NIH HHS P30 DK072517
6 · The paper itself

Abstract

Lung transplantation can be lifesaving in end-stage cystic fibrosis (CF), but long-term survival is limited by chronic lung allograft dysfunction (CLAD). Persistent upper airway

Indexed as

AdultAgedCohort StudiesCystic FibrosisEpithelial CellsFemaleGene ExpressionHumansInterferonsLungLung TransplantationMaleMicrobiotaMiddle AgedPseudomonas aeruginosaPseudomonas InfectionsInterferons

Identifiers

PMID32754722
PMCPMC7402593
OpenAlexW3045073558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.