Evidence map›Paper›PMID 32754590›Full record

ArticleFrontiers in cell and developmental biology2020

Jens H Westhoff, Petrus J Steenbergen, Laurent S V Thomas, Jana Heigwer, Thomas Bruckner, Ledean Cooper, Burkhard Tönshoff, Georg F Hoffmann, Jochen Gehrig

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Frontiers in cell and developmental biology · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Frontiers in cell and developmental biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jens H WesthoffDepartment of Pediatrics I, University Children's Hospital, Heidelberg, Germany.
Petrus J SteenbergenDepartment of Pediatrics I, University Children's Hospital, Heidelberg, Germany.
Laurent S V ThomasDepartment of Pediatrics I, University Children's Hospital, Heidelberg, Germany.
Jana HeigwerDepartment of Pediatrics I, University Children's Hospital, Heidelberg, Germany.
Thomas BrucknerInstitute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.
Ledean CooperACQUIFER Imaging GmbH, Heidelberg, Germany.
Burkhard TönshoffDepartment of Pediatrics I, University Children's Hospital, Heidelberg, Germany.
Georg F HoffmannDepartment of Pediatrics I, University Children's Hospital, Heidelberg, Germany.
Jochen GehrigDITABIS, Digital Biomedical Imaging Systems AG, Pforzheim, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEZimmer Biomet (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite widespread drug exposure, for example during gestation or in prematurely born children, organ-specific developmental toxicity of most drugs is poorly understood. Developmental and functional abnormalities are a major cause of kidney diseases during childhood; however, the potential causal relationship to exposure with nephrotoxic drugs during nephrogenesis is widely unknown. To identify developmental nephrotoxic drugs in a large scale, we established and performed an automated high-content screen to score for phenotypic renal alterations in the

Indexed as

developmentkidneypronephrosscreeningtoxicologyzebrafish

Identifiers

PMID32754590
PMCPMC7366291
OpenAlexW3040938426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.