ArticleJournal of family medicine and primary care2020
Postoperative pain, edema and trismus following third molar surgery - A comparitive study between submucosal and intravenous dexamethasone.
Article in Journal of family medicine and primary care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- The effect of Kinesio taping on postoperative complications following mandibular third molar surgery/extraction: a systematic review and meta-analysis of randomized controlled trials.Frontiers in dental medicine · 2025Pooled it
- Comparison of Submucosal With Intramuscular or Intravenous Administration of Dexamethasone for Third Molar Surgeries: A Systematic Review and Meta-Analysis.Frontiers in surgery · 2021Pooled it
- Does Kinesio taping and/or transdermal diclofenac patch reduce postoperative pain and swelling after open reduction and internal fixation of mandibular angle fractures?Oral and maxillofacial surgery · 2025Trial
- Green tea and hyaluronic acid gel enhance fibroblast activation and improves the gingival healing post-third molar extraction.Scientific reports · 2024Trial
- Postoperative Oral Dexamethasone and Its Effects on Pain, Trismus, and Quality of Life After Impacted Mandibular Third Molar Surgery: A Randomized Triple-Blind Split-Mouth Clinical Trial.Journal of clinical and experimental dentistry · 2026Review
- Association Between Mandibular Third Molar Position and Recurrent Pericoronitis: Protocol for a Cross-Sectional Study.JMIR research protocols · 2026Article
- Article
- The Role of Inflammatory Biomarkers (IL-1, IL-6, TNF-α, and Alpha-Amylase) in Saliva on Post-Odontectomy Swelling: A Rapid Review.Journal of inflammation research · 2025Review
- Evaluation of postoperative trismus in buccal versus lingual approach for impacted mandibular third molar removal.Bioinformation · 2025Article
- Effectiveness of Lidocaine with Epinephrine Irrigation in Reducing Acute Pain from Surgical Removal of Mesioangular-Impacted Third Molars.Dentistry journal · 2024Article
- Comparison of perineural and systemic dexamethasone use in impacted third molar surgeries in terms of anesthesia duration and postoperative complaints: a controlled, randomized observational study.BMC oral health · 2024Observational
- Impact of Pericoronary Microbiota Composition on Course of Recovery after Third Molar Alveotomy.Life (Basel, Switzerland) · 2024Article
- Comparing pre- and postoperative etoricoxib administration versus only postoperative on third molar extraction sequelae and oral health quality of life: a prospective quasi-experimental study.Clinical oral investigations · 2024Article
- A comparative evaluation of the effect of addition of 8 mg dexamethasone to 2% lignocaine with adrenaline in mandibular third molar surgery: a split mouth randomised double blind study.Frontiers in oral health · 2024Article
- Effect of intrasocket application of hyaluronic acid on pain, swelling, and trismus after surgical extraction of impacted mandibular third molar - A randomized control trial.National journal of maxillofacial surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThird molar surgey always needs primary intervention as it can lead to various complications and pathologies. Considering other ways for postoperative anesthesia it was infered that submucosal group which showed simple injection technique and direct surgical site administration is more beneficial. It was noticed as a patient comfort method which can be the preferred as the drug of choice over intravenous route of dexamethasone injection.
introductionImpaction of third molar is a common affliction and surgical removal is the only treatment option. The post-operative sequelae following the third molar surgery are pain, edema and trismus. The use of corticosteroids is to counteract it via various routes. Still, controversy exists in the literature regarding the administration of corticosteroids over the routes and time of administration. The purpose of this study was to compare the postoperative pain, edema and trismus following third molar surgery while using preoperative intravenous and submucosal routes of dexamethasone, in terms of pain, facial swelling, and trismus. MATERIALS AND
methodsThis study consisted of 64 patients presented with mesioangular impacted mandibular third molar for surgical removal. Preoperative measurements of edema, trismus were analyzed. Postoperative pain was estimated using visual analogue scale. Edema was assessed by the extra oral facial measurements. Trismus was measured by recording the interincisal opening in millimeters. Dexamethasone was administered intravenously or submucosally according to the choice of operating surgeon and were divided into 2 groups.
resultsMean and standard deviation calculated for continuous variables. Changes in parameters was analysed using t test and Mann-Whitney U test. Here, submucosal group were reported with increased pain on the second postoperative day. On seventh postoperative day mean value turns to 0.7 ± 1 for submucosal and 0.6 ± 1.2 for intravenous group. On overall observation, intravenous group expressed statistically significant (
conclusionAnalyzing the previous studies, and from the experience of the present one, it could be reasonably found out that administration of submucosal dexamethasone is beneficial for overall patient compliance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.