Evidence map›Paper›PMID 32754344›Full record

ReviewCanadian journal of kidney health and disease2020

Efficacy and Safety of Surgical Kidney Stone Interventions in Autosomal Dominant Polycystic Kidney Disease: A Systematic Review.

Vinusha Kalatharan, Racquel Jandoc, Gary Grewal, Danielle M Nash, Blayne Welk, Sisira Sarma, York Pei, Amit X Garg

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Canadian journal of kidney health and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vinusha KalatharanDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.ORCID https://orcid.org/0000-0001-7431-8087
Racquel JandocICES, London, ON, Canada.
Gary GrewalDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.
Danielle M NashDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.
Blayne WelkDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.
Sisira SarmaDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.
York PeiDivision of Nephrology, University Health Network and University of Toronto, ON, Canada.
Amit X GargDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.ORCID https://orcid.org/0000-0003-3398-3114
Western University · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReduced kidney function and distorted kidney anatomy in patients with autosomal dominant polycystic kidney disease (ADPKD) may complicate stone interventions more compared with the general population.

objectivesTo review studies describing the safety and efficacy of the 3 main stone interventions in adults with ADPKD: shock wave lithotripsy (SWL), ureteroscopy, and percutaneous nephrolithotomy (PCNL).

designSystematic review.

settingAny country of origin. PATIENTS: Adults with ADPKD who underwent SWL, ureteroscopy, or PCNL. MEASUREMENTS: Being stone free after the intervention and postoperative complications as reported by each study, which included pain, bleeding, and fever.

methodsRelevant studies published until February 2019 were identified through a comprehensive search of MEDLINE, EMBASE, Web of Science, BIOSIS PREVIEW, and CINAHL. Studies were eligible for review if they reported at least one outcome following SWL, ureteroscopy, and/or PCNL in adults with ADPKD. We then abstracted information on study characteristics, patient characteristics, intervention details, and postintervention outcomes and assessed the methodological quality of each study using a modified Downs and Black checklist.

resultsWe screened 221 citations from which we identified 24 studies that met our review criteria. We identified an additional article when manually reviewing the reference list of an included article, yielding a total of 25 studies describing 311 patients (32 SWL, 42 ureteroscopy, and 237 PCNL). The percentage of patients who were stone free after 1 session ranged from 0% to 69% after SWL, 73% to 100% after ureteroscopy, and 45% to 100% after PCNL. The percentage of patients with ADPKD that experienced at least one postoperative complication ranged from 0% to 33% for SWL, 0% to 27% for ureteroscopy, and 0% to 100% for PCNL. LIMITATIONS: The number and quality of studies published to date are limited.

conclusionsThe efficacy and safety of stone interventions in patients with ADPKD remains uncertain, with wide-ranging estimates reported in the literature.

trial registrationWe did not register the protocol of this systematic review.

Indexed as

autosomal dominant polycystic kidney diseasekidney stonespercutaneous nephrolithotomyshock wave lithotripsyureteroscopy

Identifiers

PMID32754344
PMCPMC7378961
OpenAlexW3044742330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.