ArticleTheranostics2020
Immunomodulation of intracranial melanoma in response to blood-tumor barrier opening with focused ultrasound.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 37 citations in OpenAlex.
- Focused ultrasound for enhancing cell-based immunotherapies in neuro-oncology.Neuro-oncology advances · 2026Review
- Ultrasound-Enhanced Drug Delivery in Pediatric Neuro-Oncology: A New Therapeutic Strategy.Pharmaceutics · 2026Review
- Porous Baicalin-Fe(III) ICP@Propofol nanocomposites for enhanced anesthetic efficacy and reduced toxicity via neuroprotection and ultrasound assistance.Asian journal of pharmaceutical sciences · 2026Article
- Focused ultrasound-microbubble treatment arrests the growth and formation of cerebral cavernous malformations.Nature biomedical engineering · 2025Article
- Imaging of brain metastases treated with immune checkpoint inhibitors.Immunotherapy · 2025Article
- Advances in brain-targeted delivery strategies and natural product-mediated enhancement of blood-brain barrier permeability.Journal of nanobiotechnology · 2025Review
- Shear Stress and Microbubble-Mediated Modulation of Endothelial Cell Immunobiology.Small science · 2025Article
- Focused Ultrasound: Noninvasive Image-Guided Therapy.Investigative radiology · 2025Review
- ATP released by ultrasound targeted microbubble cavitation induces vascular inflammation and improves immune checkpoint blockade efficacy.Theranostics · 2025Article
- Differential T cell accumulation within intracranial and subcutaneous melanomas is associated with differences in intratumoral myeloid cells.Cancer immunology, immunotherapy : CII · 2024Article
- Pulsed focused ultrasound alters the proteomic profile of the tumor microenvironment in a syngeneic mouse model of glioblastoma.Journal of neuro-oncology · 2024Article
- Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier.Nature communications · 2024Article
- Fundamentals and Applications of Focused Ultrasound-Assisted Cancer Immune Checkpoint Inhibition for Solid Tumors.Pharmaceutics · 2024Review
- Molecular signaling network and therapeutic developments in breast cancer brain metastasis.Advances in cancer biology - metastasis · 2023Article
- Barriers to immune cell infiltration in tumors.Journal for immunotherapy of cancer · 2023Review
- Ultrasound-targeted microbubble destruction remodels tumour microenvironment to improve immunotherapeutic effect.British journal of cancer · 2023Review
- Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy.Frontiers in oncology · 2023Article
- Article
- Using focused ultrasound to modulate microglial structure and function.Frontiers in cellular neuroscience · 2023Review
- Applications of focused ultrasound-mediated blood-brain barrier opening.Advanced drug delivery reviews · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Colleen T CurleyDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA.
Aaron D StevensDepartment of Pathology, University of Virginia, Charlottesville, VA.
Alexander S MathewDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA.
Katarzyna StasiakCarter Immunology Center and Department of Microbiology, Immunology, and Cancer Biology, Charlottesville, VA.
William J GarrisonDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA.
G Wilson MillerDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA.
Natasha D SheybaniDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA.
Victor H EngelhardCarter Immunology Center and Department of Microbiology, Immunology, and Cancer Biology, Charlottesville, VA.
Timothy N J BullockDepartment of Pathology, University of Virginia, Charlottesville, VA.
Richard J PriceDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA.
University of Virginia · US
Funding
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2MSupplement - Manipulating microenvironment and vasculature to enhance T cell infiltration into tumorsR01CA233716 · NCI · UNIVERSITY OF VIRGINIA · PI ENGELHARD, VICTOR H, KELLY, KIMBERLY A. · 2019 to 2023
$2.9MImmunotherapeutic Nanoparticle Delivery to Melanoma With MR-Guided Focused UltrasoundR01CA197111 · NCI · UNIVERSITY OF VIRGINIA · PI BULLOCK, TIMOTHY N, ENGELHARD, VICTOR H · 2015 to 2019
$2.6MMRI-Guided miRNA Nanoparticle Delivery to Glioblastoma With Focused UltrasoundR01EB020147 · NIBIB · UNIVERSITY OF VIRGINIA · PI HANES, JUSTIN S., PRICE, RICHARD J. · 2015 to 2018
$2.4MTransdisciplinary Big Data Science Training at UVaT32LM012416 · NLM · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, LOUGHRAN, THOMAS P. · 2016 to 2020
$1.3MLeveraging MR-Guided Focused Ultrasound to Potentiate Immunotherapy for GBMR21CA226607 · NCI · UNIVERSITY OF VIRGINIA · PI BULLOCK, TIMOTHY N · 2019 to 2020
$383kFocused Ultrasound and Multifunctional Nanoparticle Vaccines as Adjuvant Strategies for Cancer ImmunotherapyF99CA234954 · NCI · UNIVERSITY OF VIRGINIA · PI SHEYBANI, NATASHA DIBA · 2018 to 2019
$81kNCI NIH HHS F99 CA234954NCI NIH HHS R01 CA197111NCI NIH HHS R01 CA233716NCI NIH HHS R21 CA226607NIAID NIH HHS T32 AI007496NIBIB NIH HHS R01 EB020147NLM NIH HHS T32 LM012416
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsBlood-Brain BarrierBrain NeoplasmsDendritic CellsGene Expression Regulation, NeoplasticMaleMelanoma, ExperimentalMiceMicrobubblesOvalbuminSequence Analysis, RNATumor MicroenvironmentUltrasonic TherapyXenograft Model Antitumor AssaysOvalbuminblood-tumor barrierfocused ultrasoundimmune cellsinflammationRNA sequencing
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.